Vps33b (NM_178070) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209450L3V
- LentiORF®
Lenti ORF particles, Vps33b (Myc-DDK-tagged) - Mouse vacuolar protein sorting 33B (yeast) (Vps33b), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Vps33b |
Synonyms | MGC36556 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_178070 |
ORF Size | 1854 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209450).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_178070.2, NP_835171.1, NP_835171.2 |
RefSeq Size | 2595 bp |
RefSeq ORF | 1854 bp |
Locus ID | 233405 |
UniProt ID | P59016 |
Cytogenetics | 7 D2 |
Gene Summary | May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating in part VIPAS39 (By similarity). In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependentrecycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (PubMed:25947942).[UniProtKB/Swiss-Prot Function] |
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