Unc93b1 (NM_019449) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209291L3V

Lenti ORF particles, Unc93b1 (Myc-DDK-tagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Unc93b1
• Synonyms: Unc-93B1; Unc93b
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_019449
• ORF Size: 1797 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR209291).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019449.1, NP_062322.1
• RefSeq Size: 2277 bp
• RefSeq ORF: 1860 bp
• Locus ID: 54445
• UniProt ID: Q8VCW4
• Cytogenetics: 19 A
• Gene Summary: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.[UniProtKB/Swiss-Prot Function]