Nr2c1 (NM_011629) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209201L4V

Lenti ORF particles, Nr2c1 (GFP-tagged) - Mouse nuclear receptor subfamily 2, group C, member 1 (Nr2c1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Nr2c1
• Synonyms: 80.3; 4831444H07Rik; Eenr; TR2; Tr2-11
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_011629
• ORF Size: 1773 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR209201).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011629.2, NP_035759.3
• RefSeq Size: 3827 bp
• RefSeq ORF: 1773 bp
• Locus ID: 22025
• UniProt ID: Q505F1
• Cytogenetics: 10 48.81 cM
• Gene Summary: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes including ESR1 and RARB. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity). Also activator of OCT4 gene expression. Plays a fundamental role in early embryogenesis and regulates embryonic stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.[UniProtKB/Swiss-Prot Function]