Mef2a (NM_001033713) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207994L1V

Lenti ORF particles, Mef2a (Myc-DDK-tagged) - Mouse myocyte enhancer factor 2A (Mef2a), 200ul, >10^7 TU/mL

Product Images

MR207994L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with MR207994L1V particle to overexpress human Mef2a-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Mef2a
• Synonyms: A430079H05Rik
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001033713
• ORF Size: 1494 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR207994).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001033713.1, NP_001028885.1
• RefSeq Size: 2898 bp
• RefSeq ORF: 1497 bp
• Locus ID: 17258
• UniProt ID: Q60929
• Cytogenetics: 7 36.72 cM
• Gene Summary: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter (By similarity).[UniProtKB/Swiss-Prot Function]