Rrm2b (NM_199476) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR205344L3V

Lenti ORF particles, Rrm2b (Myc-DDK-tagged) - Mouse ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Rrm2b
• Synonyms: p53R2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_199476
• ORF Size: 1056 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR205344).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_199476.1, NP_955770.1
• RefSeq Size: 4532 bp
• RefSeq ORF: 1056 bp
• Locus ID: 382985
• UniProt ID: Q6PEE3
• Cytogenetics: 15 B3.1
• Gene Summary: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.[UniProtKB/Swiss-Prot Function]