RPS6KC1 (NM_001287219) Human Untagged Clone

CAT#: SC337583

RPS6KC1 (untagged) - Human ribosomal protein S6 kinase, 52kDa, polypeptide 1 (RPS6KC1), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RPS6KC1
• Synonyms: humS6PKh1; RPK118; RSKL1; S6K-delta-1; S6PKh1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001287219, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTTCCAATCAAAATTCTCCCATTAGAACTTTTGGTCTCAATCTTTCTTCGGATTCTTCAGCACTAG
  GGGCTGTTGCTTCTGACAGTGAACAGAGCAAAACAGAAGAAGAACGGGAAAGTCGTAGCCTCTTTCCTGG
  CAGTTTAAAGCCGAAGCTTGGCAAGAGAGATTATTTGGAGAAAGCAGGAGAATTAATAAAGCTGGCTTTA
  AAAAAGGAAGAAGAAGACGACTATGAAGCTGCTTCTGATTTTTATAGGAAGGGAGTTGATTTACTCCTAG
  AAGGTGTTCAAGGAGAGTCAAGCCCTACCCGTCGAGAAGCTGTGAAGAGAAGAACAGCCGAGTACCTCAT
  GCGGGCAGAAAGTATCTCTAGTCTTTATGGGAAACCTCAGCTTGATGATGTATCTCAGGTTTTACTTGTA
  ATGGACACAAGGACAGAACAGACTTTCATTTTAAAAGGTCTAAGGAAAAGCAGTGAATACAGCAGGAACA
  GAAAGACCATCATCCCCCGCTGTGTGCCCAACATGGTGTGTCTGCATAAGTACATCATCTCTGAGGAGTC
  AGTATTTCTTGTGCTGCAGCATGCGGAAGGTGGCAAACTGTGGTCATATATCAGTAAATTTCTAAACAGA
  AGTCCTGAAGAAAGCTTTGACATCAAGGAAGTGAAAAAACCTACACTTGCAAAAGTTCACCTGCAGCAGC
  CAACTTCTAGTCCTCAGGACAGCAGTAGCTTTGAATCCAGAGGAAGTGATGGTGGAAGCATGCTTAAAGC
  TCTGCCTTTGAAGAGTAGTCTTACTCCAAGTTCTCAAGATGACAGCAACCAGGAAGATGATGGCCAAGAT
  AGCTCTCCAAAGTGGCCAGATTCTGGTTCAAGTTCAGAAGAAGAATGTACTACTAGTTATTTAACATTAT
  GCAATGAATATGGGCAAGAAAAGATTGAACCAGGGTCTTTGAATGAGGAGCCCTTCATGAAGACTGAAGG
  GAATGGTGTTGATACAAAAGCTATTAAAAGCTTCCCAGCACACCTTGCTGCTGACAGTGACAGCCCCAGC
  ACACAGCTGAGAGCTCACGAGCTGAAGTTCTTCCCCAACGATGACCCAGAAGCAGTTAGTTCTCCAAGAA
  CATCAGATTCCCTCAGTAGATCAAAAAATAGCCCCATGGAATTCTTTAGGATAGACAGTAAGGATAGCGC
  AAGTGAACTCCTGGGACTTGACTTTGGAGAAAAATTGTATAGTCTAAAATCAGAACCTTTGAAACCATTC
  TTTACTCTTCCAGATGGAGACAGTGCTTCTAGGAGTTTTAATACTAGTGAAAGCAAGGTAGAGTTTAAAG
  CTCAGGACACCATTAGCAGGGGCTCAGATGACTCAGTGCCAGTTATTTCATTTAAAGATGCTGCTTTTGA
  TGATGTCAGTGGTACTGATGAAGGAAGACCTGATCTTCTTGTAAATTTACCTGGTGAATTGGAGTCAACA
  AGAGAAGCTGCAGCAATGGGACCTACTAAGTTTACACAAACTAATATAGGGATAATAGAAAATAAACTCT
  TGGAAGCCCCTGATGTTTTATGCCTCAGGCTTAGTACTGAACAATGCCAAGCACATGAGGAGAAAGGCAT
  AGAGGAACTGAGTGATCCCTCTGGGCCCAAATCCTATAGTATAACAGAGAAACACTATGCACAGGAGGAT
  CCCAGGATGTTATTTGTAGCAGCTGTTGATCATAGTAGTTCAGGAGATATGTCTTTGTTACCCAGCTCAG
  ATCCTAAGTTTCAAGGACTTGGAGTGGTTGAGTCAGCAGTAACTGCAAACAACACAGAAGAAAGCTTATT
  CCGTATTTGTAGTCCACTCTCAGGTGCTAATGAATATATTGCAAGCACAGACACTTTAAAAACAGAAGAA
  GTATTGCTGTTTACAGATCAGACTGATGATTTGGCTAAAGAGGAACCAACTTCTTTATTCCAGAGAGACT
  CTGAGACTAAGGGTGAAAGTGGTTTAGTGCTAGAAGGAGACAAGGAAATACATCAGATTTTTGAGGACCT
  TGATAAAAAATTAGCACTAGCCTCCAGGTTTTACATCCCAGAGGGCTGCATTCAAAGATGGGCAGCTGAA
  ATGGTGGTAGCCCTTGATGCTTTACATAGAGAGGGAATTGTGTGCCGCGATTTGAACCCAAACAACATCT
  TATTGAATGATAGAGGACACATTCAGCTAACGTATTTTAGCAGGTGGAGTGAGGTTGAAGATTCCTGTGA
  CAGCGATGCCATAGAGAGAATGTACTGTGCCCCAGAGGTTGGAGCAATCACTGAAGAAACTGAAGCCTGT
  GATTGGTGGAGTTTGGGTGCTGTCCTCTTTGAACTTCTCACTGGCAAGACTCTGGTTGAATGCCATCCAG
  CAGGAATAAATACTCACACTACTTTGAACATGCCAGAATGTGTCTCTGAAGAGGCTCGCTCACTCATTCA
  ACAGCTCTTGCAGTTCAATCCTCTGGAACGACTTGGTGCTGGAGTTGCTGGTGTTGAAGATATCAAATCT
  CATCCATTTTTTACCCCTGTGGATTGGGCAGAACTGATGAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001287219
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001287219.1, NP_001274148.1
• RefSeq Size: 4243 bp
• RefSeq ORF: 2565 bp
• Locus ID: 26750
• Cytogenetics: 1q32.3
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (4) differs in its 5' UTR, initiates translation at a downstream start codon, and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a. Variants 3, 4, and 15 all encode the same isoform (c). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.