ERBIN (NM_001253699) Human Untagged Clone
CAT#: SC332218
ERBB2IP (untagged) - Homo sapiens erbb2 interacting protein (ERBB2IP), transcript variant 8
"NM_001253699" in other vectors (2)
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Frequently bought together (4)
Other products for "ERBIN"
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | ERBIN |
Synonyms | ERBB2IP; HEL-S-78; LAP2 |
Vector | pCMV6-Entry |
Sequence Data |
>SC332218 representing NM_001253699.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGACTACAAAACGAAGTTTGTTTGTGCGGTTGGTACCATGTCGCTGTCTACGAGGGGAAGAGGAGACT GTCACTACTCTTGATTATTCTCATTGCAGCTTAGAACAAGTTCCGAAAGAGATTTTTACTTTTGAAAAA ACCTTGGAGGAACTCTATTTAGATGCTAATCAGATTGAAGAGCTTCCAAAGCAACTTTTTAACTGTCAG TCTTTACACAAACTGAGTTTGCCAGACAATGATTTAACAACGTTACCAGCATCCATTGCAAACCTTATT AATCTCAGGGAACTGGATGTCAGCAAGAATGGAATACAGGAGTTTCCAGAAAATATAAAAAATTGTAAA GTTTTGACAATTGTGGAGGCCAGTGTAAACCCTATTTCCAAGCTCCCTGATGGATTTTCTCAGCTGTTA AACCTAACCCAGTTGTATCTGAATGATGCTTTTCTTGAGTTCTTGCCAGCAAATTTTGGCAGATTAACT AAACTCCAAATATTAGAGCTTAGAGAAAACCAGTTAAAAATGTTGCCTAAAACTATGAATAGACTGACC CAGCTGGAAAGACTGGATTTGGGAAGTAACGAATTCACGGAAGTGCCTGAAGTACTTGAGCAACTAAGT GGATTGAAAGAGTTTTGGATGGATGCTAATAGACTGACTTTTATTCCAGGGTTTATTGGTAGTTTGAAA CAGCTCACATATTTGGATGTTTCTAAAAATAATATTGAAATGGTTGAAGAAGGAATTTCAACATGTGAA AACCTTCAAGACCTCCTATTATCAAGCAATTCACTTCAGCAGCTTCCTGAGACTATTGGTTCGTTGAAG AATATAACAACGCTTAAAATAGATGAAAACCAGTTAATGTATCTGCCAGACTCTATAGGAGGGTTAATA TCAGTAGAAGAACTGGATTGTAGTTTCAATGAAGTTGAAGCTTTGCCTTCATCTATTGGGCAGCTTACT AACTTAAGAACTTTTGCTGCTGATCATAATTACTTACAGCAGTTGCCCCCAGAGATTGGAAGCTGGAAA AATATAACTGTGCTGTTTCTCCATTCCAATAAACTTGAGACACTTCCAGAGGAAATGGGTGATATGCAA AAATTAAAAGTCATTAATTTAAGTGATAATAGATTAAAGAATTTACCCTTTAGCTTTACAAAGCTACAG CAATTGACAGCTATGTGGCTCTCAGATAATCAGTCCAAACCCCTGATACCTCTTCAAAAAGAAACTGAT TCAGAGACCCAGAAAATGGTGCTTACCAACTACATGTTCCCTCAACAGCCAAGGACTGAGGATGTTATG TTTATATCAGATAATGAAAGTTTTAACCCTTCATTGTGGGAGGAACAGAGGAAACAGCGGGCTCAAGTT GCATTTGAATGTGATGAAGACAAAGATGAAAGGGAGGCACCTCCCAGGGAGGGAAATTTAAAAAGATAT CCAACACCATACCCAGATGAGCTTAAGAATATGGTCAAAACTGTTCAAACCATTGTACATAGATTAAAA GATGAAGAGACCAATGAAGACTCAGGAAGAGATTTGAAACCACATGAAGATCAACAAGATATAAATAAA GATGTGGGTGTGAAGACCTCAGAAAGTACTACTACAGTAAAAAGCAAAGTTGATGAAAGAGAAAAATAT ATGATAGGAAACTCTGTACAGAAGATCAGTGAACCTGAAGCTGAGATTAGTCCTGGGAGTTTACCAGTG ACTGCAAATATGAAAGCCTCTGAGAACTTGAAGCATATTGTTAACCATGATGATGTTTTTGAGGAATCT GAAGAACTTTCTTCTGATGAAGAGATGAAAATGGCGGAGATGCGACCACCATTAATTGAAACCTCTATT AACCAGCCAAAAGTCGTAGCACTTAGTAATAACAAAAAAGATGATACAAAGGAAACAGATTCTTTATCA GATGAAGTTACACACAATAGCAATCAGAATAACAGCAATTGTTCTTCTCCATCTCGGATGTCTGATTCA GTTTCTCTTAATACTGATAGTAGTCAAGACACCTCACTCTGCTCTCCAGTGAAACAAACTCATATTGAT ATTAATTCCAAAATCAGGCAAGAAGATGAAAATTTTAACAGCCTTTTACAAAATGGAGATATTTTAAAC AGTTCAACAGAGGAAAAGTTCAAAGCTCATGATAAAAAAGATTTTAACTTACCTGAATATGATTTGAAT GTTGAAGAGCGATTAGTTCTAATTGAGAAAAGTGTTGACTCAACAGCCACAGCTGATGACACTCACAAA TTAGATCATATCAATATGAATCTTAATAAACTTATAACTAATGATACATTTCAACCAGAGATCATGGAA AGATCAAAAACACAGGATATTGTGCTTGGAACAAGCTTTTTAAGCATTAATTCTAAAGAGGAAACTGAG CACTTGGAAAATGGAAACAAGTATCCTAATTTGGAATCCGTAAATAAGGTAAATGGACATTCTGAGGAA ACTTCCCAGTCTCCTAATAGGACTGAACCACATGACAGTGATTGTTCTGTTGACTTAGGTATTTCCAAA AGCACTGAAGATCTCTCCCCTCAGAAAAGTGGTCCAGTTGGATCTGTTGTGAAATCTCATAGCATAACT AATATGGAGATTGGAGGGCTAAAAATCTATGATATTCTTAGTGATAATGGACCTCAGCAGCCAAGTACA ACCGTTAAAATCACATCTGCTGTTGATGGAAAAAATATAGTCAGGAGCAAGTCTGCCACACTGTTGTAT GATCAACCATTGCAGGTATTTACTGGTTCTTCCTCATCTTCTGATTTAATATCAGGAACAAAGGCAATT TTCAAGTTTGATTCAAATCATAATCCCGAAGAGCCAAATATAATAAGAGGCCCCACAAGTGGCCCACAA TCTGCACCTCAAATATATGGTCCTCCACAGTATAATATCCAATACAGTAGCAGTGCTGCAGTCAAAGAC ACTTTGTGGCACTCCAAACAAAATCCCCAAATAGACCATGCCAGTTTTCCTCCTCAGCTCCTTCCTAGA TCAGAGAGCACAGAAAATCAAAGTTATGCTAAACATTCTGCCAATATGAATTTCTCTAATCATAACAAT GTTCGAGCTAATACTGCATACCATTTACATCAGAGACTTGGCCCAGCAAGACATGGGGAAATGTGGGCC ATCTCACCAAACGACCGACTTATTCCTGCAGTAACTCGAAGTACAATCCAGCGACAAAGTAGTGTGTCC TCCACAGCCTCTGTAAATCTTGGTGATCCAGGCTCTACAAGGCGGGCTCAGATTCCTGAAGGAGATTAT TTATCATACAGAGAGTTCCACTCAGCGGGAAGAACTCCTCCAATGATGCCAGGATCACAGAGACCCCTT TCTGCACGAACATACAGCATAGATGGTCCAAATGCATCAAGACCTCAGAGTGCTCGACCCTCTATTAAT GAAATACCAGAGAGAACTATGTCAGTTAGTGATTTCAATTATTCACGGACTAGTCCTTCAAAAAGACCA AATGCAAGGGTTGGTTCTGAGCATTCTTTATTAGATCCTCCAGGAAAAAGTAAAGTTCCTCGTGACTGG AGAGAACAAGTACTTCGACATATTGAAGCCAAAAAGTTAGAAAAGAGCATGCTGTCAAGGTCCTTTAAT TCCAATTTTACTACTGTAAGCAGTTTTCACTGTGGCAGCTCTAGGGATCTGCATGGCAGCCAGGGCAGT CTTGCCTTGAGTGTTGCAGACAGAAGAGGTTCTGGTGGGCACATTTTTCGAATGCCTTTGAGTAATGGA CAGATGGGCCAGCCTCTCAGGCCTCAGGCAAATTATAGTCAAATACATCACCCCCCTCAGGCATCTGTG GCAAGGCATCCCTCTAGAGAACAACTAATTGATTACTTGATGCTGAAAGTGGCCCACCAGCCTCCATAT ACACAGCCCCATTGTTCTCCTAGACAAGGCCATGAACTGGCAAAACAAGAGATTCGAGTGAGGGTTGAA AAGGATCCAGAACTTGGATTTAGCATATCAGGTGGTGTCGGGGGTAGAGGAAACCCATTCAGACCTGAT GATGATGGTATATTTGTAACAAGGGTACAACCTGAAGGACCAGCATCAAAATTACTGCAGCCAGGTGAT AAAATTATTCAGGCTAATGGCTACAGTTTTATAAATATTGAACATGGACAAGCAGTGTCCTTGCTAAAA ACTTTCCAGAATACAGTTGAACTCATCATTGTACGAGAAGTTTCCTCATAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001253699 |
Insert Size | 4260 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001253699.1 |
RefSeq Size | 7063 bp |
RefSeq ORF | 4260 bp |
Locus ID | 55914 |
UniProt ID | Q96RT1 |
Cytogenetics | 5q12.3 |
Protein Families | Druggable Genome |
Protein Pathways | NOD-like receptor signaling pathway |
MW | 159 kDa |
Gene Summary | This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] Transcript Variant: This variant (8) lacks an exon and includes an alternate exon in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (8) is longer than isoform 1. |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.