ASC 2 (NCOA6) (NM_001242539) Human Untagged Clone

CAT#: SC331826

NCOA6 (untagged) - Homo sapiens nuclear receptor coactivator 6 (NCOA6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ASC 2
• Synonyms: AIB3; ASC2; NRC; PRIP; RAP250; TRBP
• Vector: pCMV6-Entry
• Sequence Data:
  Fully Sequenced ORF

  >SC331826 representing NM_001242539.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  ATGGTTTTGGATGACCTTCCAAACTTAGAAGACATCTATACTTCCTTGTGTTCATCAACAATGGAAGAC
  TCAGAGATGGATTTTGACTCTGGACTAGAAGATGATGACACAAAAAGTGATAGTATTTTGGAGGATTCC
  ACAATTTTTGTGGCCTTCAAAGGAAATATAGATGATAAAGACTTCAAATGGAAATTAGATGCAATATTG
  AAAAACGTGCCCAATTTGTTACACATGGAGTCCAGCAAGCTAAAAGTACAGAAGGTGGAGCCCTGGAAC
  AGCGTGCGTGTGACATTCAACATCCCCCGGGAAGCAGCGGAGCGGCTACGGATCCTTGCTCAGAGCAAC
  AACCAGCAGCTTCGGGATTTAGGGATTCTCTCCGTTCAGATTGAAGGGGAAGGTGCTATTAACCTGGCT
  TTGGCTCAGAACCGAAGCCAAGATGTGAGAATGAATGGACCCATGGGAGCTGGAAATTCAGTTAGGATG
  GAGGCGGGATTTCCTATGGCAAGTGGTCCAGGAATAATAAGGATGAACAACCCTGCCACTGTTATGATA
  CCCCCGGGTGGAAATGTGTCATCTTCCATGATGGCACCAGGCCCCAATCCAGAGCTGCAGCCCAGGACT
  CCTCGCCCTGCTTCTCAGTCAGATGCAATGGATCCACTCCTCTCTGGGCTCCATATACAGCAGCAAAGT
  CATCCCTCAGGATCTTTAGCTCCCCCACATCACCCAATGCAGCCTGTCTCTGTGAACAGACAAATGAAC
  CCAGCTAATTTTCCCCAGCTGCAGCAGCAGCAGCAACAACAACAACAGCAGCAGCAGCAGCAGCAGCAG
  CAACAACAGCAACAGCAGCAACAACAGTTGCAGGCAAGACCCCCACAGCAACATCAGCAGCAACAGCCA
  CAGGGAATTCGACCCCAGTTTACTGCCCCAACTCAGGTGCCTGTTCCTCCAGGCTGGAACCAGCTGCCT
  TCTGGAGCCCTTCAACCTCCTCCAGCCCAGGGTTCTCTGGGCACAATGACTGCAAACCAAGGGTGGAAG
  AAGGCTCCCTTGCCCGGCCCAATGCAACAGCAACTCCAGGCAAGACCATCCTTAGCCACGGTACAGACG
  CCTTCCCACCCTCCCCCTCCATATCCCTTTGGCAGCCAGCAAGCCTCACAAGCCCACACAAACTTTCCT
  CAGATGAGCAACCCAGGCCAGTTCACAGCTCCTCAGATGAAGAGTTTGCAGGGAGGGCCCTCTAGGGTC
  CCAACTCCCTTGCAGCAGCCCCACCTCACCAACAAGTCTCCTGCCTCCTCACCCTCCTCCTTCCAGCAG
  GGATCCCCTGCATCCTCCCCAACGGTTAACCAAACTCAGCAGCAGATGGGACCAAGGCCACCTCAAAAT
  AACCCACTTCCCCAGGGATTTCAGCAGCCTGTCAGCTCTCCGGGTCGGAATCCTATGGTTCAACAGGGA
  AATGTGCCACCTAACTTCATGGTGATGCAGCAGCAACCACCAAACCAGGGGCCACAGAGTTTACATCCA
  GGCCTAGGAGGAATGCCTAAACGCCTCCCACCTGGCTTCTCAGCAGGACAGGCCAATCCGAACTTTATG
  CAAGGTCAGGTGCCTTCGACCACAGCAACCACCCCTGGGAATTCAGGAGCCCCTCAGCTGCAAGCAAAT
  CAAAATGTCCAGCATGCAGGTGGTCAAGGAGCTGGTCCTCCTCAAAACCAGATGCAGGTGTCCCACGGG
  CCGCCAAATATGATGCAGCCCAGCCTCATGGGAATTCATGGCAACATGAACAATCAGCAGGCTGGTACT
  TCTGGGGTTCCTCAAGTGAACCTCAGCAACATGCAAGGCCAGCCCCAGCAGGGCCCACCATCTCAGCTG
  ATGGGCATGCACCAGCAAATCGTGCCCTCCCAGGGCCAGATGGTCCAGCAACAAGGAACCTTGAACCCT
  CAGAACCCTATGATCCTTTCAAGGGCCCAGCTTATGCCACAGGGCCAGATGATGGTGAACCCCCCGAGC
  CAAAATCTTGGGCCCTCGCCCCAAAGGATGACCCCACCCAAGCAGATGCTTTCCCAGCAGGGCCCACAA
  ATGATGGCGCCACATAACCAGATGATGGGGCCTCAGGGGCAGGTTTTGCTCCAACAGAACCCAATGATA
  GAGCAGATTATGACCAATCAAATGCAGGGGAATAAGCAGCAGTTTAACACTCAGAACCAGTCCAATGTC
  ATGCCGGGACCAGCCCAGATAATGAGGGGACCAACTCCAAACATGCAAGGAAATATGGTGCAGTTTACG
  GGACAGATGTCAGGACAGATGCTGCCCCAGCAAGGGCCTGTGAACAACAGTCCATCTCAGGTTATGGGC
  ATTCAGGGACAGGTCCTGCGGCCACCAGGGCCCAGCCCACACATGGCCCAGCAGCATGGTGATCCTGCT
  ACTACAGCAAATAACGATGTCAGTTTATCTCAGATGATGCCTGATGTTAGCATTCAACAAACCAACATG
  GTCCCCCCTCATGTGCAGGCCATGCAGGGAAACAGTGCCTCGGGAAACCACTTCTCAGGCCATGGGATG
  TCTTTCAATGCACCTTTCAGTGGAGCTCCCAATGGAAATCAGATGTCCTGTGGTCAAAATCCAGGCTTC
  CCAGTCAATAAGGATGTCACGCTAACGAGCCCATTGTTGGTCAACTTATTGCAGAGTGACATATCTGCA
  GGCCATTTTGGGGTAAACAATAAGCAAAATAATACCAACGCAAATAAACCGAAGAAGAAGAAACCCCCT
  CGGAAGAAGAAAAATAGTCAGCAAGATCTAAACACCCCAGATACTCGCCCAGCTGGTCTGGAAGAGGCT
  GATCAGCCACCGTTGCCTGGAGAACAAGGAATTAACTTGGATAACTCAGGCCCTAAACTGCCAGAATTT
  TCAAACCGGCCACCAGCCCCGTCGCAGAATTTAGTCTCAAAGGAAACTTCAACCACAGCACTGCAGGCC
  TCTGTTGCCAGACCAGAGCTGGAGGTAAATGCTGCCATAGTCTCTGGACAAAGCAGTGAGCCCAAAGAG
  ATAGTTGAAAAGTCCAAAATCCCAGGCCGAAGAAACTCCCGAACTGAAGAGCCAACTGTGGCCTCTGAA
  AGTGTGGAAAATGGACATCGTAAACGATCTTCTCGACCTGCTTCAGCCTCCAGCTCTACTAAAGACATA
  ACCAGTGCGGTGCAATCCAAGCGAAGAAAATCCAAGTAA
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001242539
• Insert Size: 3213 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001242539.1
• RefSeq Size: 4092 bp
• RefSeq ORF: 3213 bp
• Locus ID: 23054
• UniProt ID: Q14686
• Cytogenetics: 20q11.22
• Protein Families: Druggable Genome, Transcription Factors
• MW: 115.3 kDa
• Gene Summary: The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
  Transcript Variant: This variant (2) lacks an in-frame coding exon in the central coding region, compared to variant 3. The encoded isoform (2, also known as NCOA6-beta) is shorter than isoform 1.