EXPH5 (NM_001144763) Human Untagged Clone

CAT#: SC325422

EXPH5 (untagged)-Human exophilin 5 (EXPH5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXPH5
• Synonyms: SLAC2-B; SLAC2B
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001144763, the custom clone sequence may differ by one or more nucleotides
  ATGTTAAAACAACCACTTACATACAGGCTAAGTAAGGAGATGGCAAAAAATGATCCGATA
  GAATTACCTACATCAAGATCTAAAAATGTAACTAATCAAAAAAAGCCGACACCTTTTTCT
  TCCCGGATGAGCTTCAGATCGTCATTTGCTTCCCTGTTCTCATTCAGGAAATCTGGAAAG
  GAGACTTCAAAGCTTCCATCACTGGGACAGAAAGGATGTGATGGCCATGCAGGACCTCCT
  ATGCCTGTGAGGGGAGCTGCTGTGCAGGCAAAAATATACAATTCACCTCTGGAAAATCAT
  CTAGTTGACAGTACATTTGTCCCAAAGCCAGCAGTCATGAGGGAGGAGAGTGGCATGCCT
  CCACCGTGGGATGCTTCACTGCTGGAGAATGAGTTTTTCCAAGTTTTAGATGACTTGGAT
  AGCAAATTGGCTCAGGAACAGTCTGCAAGCTCAGTGAATACCAGAACACCCCTCAACTAT
  GGATCAAGAACACAGTTCGGTCACTTTTATTCCAGTGGTAACAGACATGGTAATATCACA
  GAAAGGCACAAAAAACACTATAATGAAACTTCCAATATGTCTATCTATGACATCCTAAGA
  CCAGGAACTCCTAGGGAAGGTTTTAAAACCTTTTCTCCTAGGACAAGCACAATTTATGAT
  ATGTATAGGACAAGGGAGCCCAGAGTCTTTAAAGAAGATTATGTGCAAAAGAATACTTTT
  GGCAGTACTTCGCTGTGTTTTGACAGCAGGCAACGGTCGGCCTTACCAGCCACAGGGCAT
  TTCACAGCAAGAAGCTTACATTTTCCAGCCACAACTCAGAGCAAGAGTGGGTTTATACCA
  CCAAGGCACCAGCAGAGTCCAAAGAGAACTCCTTTATCATCCATCATATGGAACAGATCA
  GATTCCTCTAGAGACAGGGAGAACCAGGAAGAGTTCCTGAGGGCACCATCACCAATGGAA
  ATTGATCCCGCTGACAAGTATGTGTATCCCAGGGGTTTTCAGGAGAATAAGAGATATGAA
  TCGTACCATTCACAGAATGTTTACCAACGTGTTAGTTTAAATGCTCCCATGGAGAATGCA
  ATGAGTCCCGACACTTTTGAGAACTCAGAGAACATGCCATTCTACCATCAAAGCAACACA
  TTTACCAGATCTTTCTTCAGCAATACCTTTGGACGAAGCGGAGAACAGAGGAGATTTGGA
  CAAGGTCCTTTTTGGGGCCAAGAGAAAGGACATTCTTTCTGGTCTGACTTTCATCGAAGC
  AGGAAATCATTCAGTTCTTCTGACAGAGACTTTGAAATGATTTCCATGGAAGCAAATAGT
  GTATCAGCCATTCATGGCCATAATGTTTCTTCTGAACACTGGGAATCATTTTCTTCTGGT
  TATGGAACAGATGTTTCCAGAGGCCAAGAAGAGCCACATCCTTGGCAGTTTGATTTTCAG
  AGATCCACACTGGATAGCATGGTGGTATCACATGGTAATGAGACCCAGTTGACTCCTCAT
  TTTGGCACACCAAATGTTTGCTCCATGACTGGTTCAAGCTATCACGTCAAATCTAGTGAG
  TTGGTAAGTCAACAGGACAGTTCTCCTGTAGAAGTACATATAAACAAAGAAGCTTCCTCA
  TTTGGAATTGCTCAGACTCTAGCATCCTCATTCAAAACTTCCTTTTCCCAGATTTCTGAT
  GACAGAAGGAATCCTCAGAGTCCCAACTTGCAGAATCCCACAGTCACTTTGCAGAAAATT
  TTTCCAAATAAGCCTGCCTCTCATCCAATGAGAAGCCATACAGAAGTCACTGTGACCAGC
  AGCAATTCAGTTGACTCTCTGCCTCTTGCCAAAAGCCAGCCCAATATCTTGGTCACAGAA
  GTAAATAATGAGAAAGACTTAAATGAATCTATTTCAGAAGAAGACAAACAGCTAAGCAAG
  ATGGACCAGACAAACAAGGCAGGTGAAATACCCCAACCTGTTTCACAGACAGGGATCTCA
  AACTCTTTACCTGATTTTCAAAATCCCTTATCCCAGGACTCAGCCAAGAGCAACGGGTTT
  GGTTTTAATGCATCTACCATAATAAGTTCAAAAAAGTCACCCAGAGTCTTTTCCAGGAAA
  GATACCTCCAAAATGTATATACCGCACACAGATAAATCCAATGACATTAAACAAGATAAG
  AGGTTTACTGAAAACAGAAAACTTGGCTCAACAGCTTCCCTTCCTTTCATTCAGGAACAC
  AGAACACCACCATCTTTCCCCAGGACAGACCAAGGTTGTCACCAGGAATTAACTGTAAAT
  AATGAAGATATTTCAAGAATTATTACAAATAACCACTGGAGCTCTGCACTGACTGATACT
  CAAAATGCACAATACTCAAAATGCAAGTTAACTCCTGGCCACAAGACCTCGTGTGATTCT
  TTAGATCTGTCATCAGCTGCACTACCAGATTCCTCACCATCAAAGAATTCTTCCCTTGAT
  GCTCCTGTGGTTCCATCTACTACAGTGTTCTCCAGGAGAAGTCCTTCAGACAAAGATCCA
  TCGCTAGGAGAAAGAGAAGAAAAAGACAATGCTGGGAAGAACCAAAAGAATCAGTTTATT
  GTAAGCCACTCAGAAAACCAAGAGAGAAATGATAGTCCTGTGCCTACACATGATGAAGTG
  GTTGATGTCAAATGCCATTCACACTCTCCTTTTAGGAATGAAAGAGGAAAAGGAAAAATA
  AGGCATCATATATCCTGTATTGAAAAGTTAAGCAAAACAGAAAGTATATCAGTACCCACC
  AGTGATCACAGGAGCCTCATTGAAGCAAATCAAAGCAATTCCAAAGTTTCTGAACTTGAC
  ACAATTTATTGTACCTTGCCAAGAAAATCAAGCAGTTTTCTCATACATGGCAGGCAGTCA
  GGAAGTAAAATAATGGCTGCTTCATTGAGGAATGGGCCACCTCCCTTCCAAATCAAAAAT
  AATGTGGAAGATGCAATGGGGAACTATATGTTAAACAAATTTAGTCCCAGTTCTCCTGAG
  TCAGCGAATGAATGTTCCAAAGTCCTTTCAGACTCAGCCCTGGAAGCACCTGAAGCCACA
  GAGAGAATGACAAATGTAAAAAGCAGTGGATCTACTTCCGTTAGAAAAGGACCACTTCCA
  TTCCTCATCAACAGGGCTATGTCATGTCCCTCAGGGGAGCCACATGCCTCAACTGGAAGA
  GAAGGAAGAAAAAAGCCATTGACCTCAGGCATGGATGCTTCTGAGCTAACACCAAGGGCT
  TGGGAGAGAATCATTAGCCCTGTGGAAAGTGACTCATCTGTTAGAGATTGTTCTTTAACC
  AAAAGACAACACCAAAAGGAAAACTTCCAAGAATACACTGAGAAAGAGGGTAAAATGGCT
  GCCTCCAGGAGAAGTGTATTTGCTCTTTCAAATGAAGACCCTTTACCTTTTTGCTCAGAC
  TTGTCAGGAAAAGAACGTGGGAAAACATTACATAAAGTTAAGACGACTAGTACGTTTTCT
  GTTTCTGGTGATGAAGATAATGTAAAATGTCTGGAGGTGGTCTCAATATATTACACTCTA
  CCGAGGAAACCCAGCAAAAAATTCTGTAACCTCCTTCAACAGTATACACAAAATACTAAT
  TTACTTATAGAATCACCTCAAGTGGAGACTGAAACATTTCCTAACGCTTTAGAAAAAGAC
  AAACAGAATTATTCTACACGAGAGCAGTCAGGAACACCTTCATGTGAAAATCTAAAGATG
  TCCGTCAACTCTGATCAGACGCTCACCACTGAAAATATGACTGCCTTCCGATTATCAAAT
  AGGGGGCCCCTAGCTCCTACATTACAGGAAATGGCTTCTGTTGAGGCAGCTGTTTCTCTT
  CCTGAAGAGGAATCTAAAGCTAGAGAGATTTTTTCAGATAATTTAGCTAAAACACCTCTA
  GGTGATTCAGAAAACAAGAAGGAAAGAGGCAAAAAGTTGCAAAGTGAAACCCTGCATACT
  TCATTGATGCTTCAGAGAAAAAATGTATCCGAAGAAAAATCTGAAAATTGTCAACAATCC
  ATTAATTCAAGTAACAGTGGTCCCTCTAGTCTTCCAGCTCTTTCAGAAGTTAATATTGGA
  AATTCCCAAACTAGAAGAAGTTCTTGGGAGTGTACAGGGAGTGGTAGAGCCATTCCATTT
  ACTGGAAGTGGCAAGTGTCCCCAGAAAGATCACACATCCACAGCTGTAGGTGATGGCTCC
  AGTGGATCACAGCCTAGGGAAGGCAGAGGGGACATTGGAACCAACTGCCAAAAAATGACT
  AATAAAACACTTTCTCACTCAGAGAGTCAAGTCTTTGCCCTTACTCCAGCATTGCATAAA
  CTACAGCTTGGTGAGGAGACTCAGTCAGATGAACCAAACTTAGAGAGTCTGCAGTCTGAA
  CCAAGAGAATTACCTCAAAGAAGTCAGGAGGCAAATATGACAGAGAGCAGGAAGGCTGAA
  GATGAAATGCAGAAGTCAGCTTGGGATCAACCTTCACTTCCTGAAGGAAACAAAAATAAA
  ACCAACTTGGATGACCTAGTAAAGGGGGAAAATAGATCTTCAGTTAAACACAGATTGGCA
  GCCATGTCTAAAGCCAGCAGAAAATTCCCAGCTAAAGATGTAAGCCCCAGAAGACATGTA
  GCTACTATCTTCCCCCAAAGTGGAAGCAGATCTGGCTTTGACCATTTATCTCTTGGCACA
  GTGGAGTGCAACCCACTGTTCCCTGAGCCTACTCCAAAATCTGCAGAGTCCATTGGCGAA
  AGCAGGTTGAGTGAGAACGGAAAGCATGTGAAGAAATCCGAGAACCTTCTCCCCATTACT
  GTACTACCCAACAGAGAACCTTCTACACACGTCAGCAACCAGAAGTCTAACAGCATTTCA
  CAACGACATCAGAATGAGTTTAAAAACGTCTCAGAATCACCATCAAAGCATGAGAATTCT
  AAAGACGTCACAGCAGCTCAGAATTTAGTAAGAGAATCAGGAGCCCCATCACCCATCACA
  TTCACCAGCCTCAGGGAAGCAGAATTCTCTGACAATCAGAGGAGGCTGAGCCCTCCTTTT
  CCACTGGAGCCTGCACAGAAATCTAGAGTAAGCAGTCCACTGGCCAGTTTTCTGCAGCAA
  CAAAGGAGTGCTTCATCTCTGGAGTGGGAACCTGAGCCACACCTCTATCGTTCAAAGAGT
  TTAAAAAGCATTAATGTTCATGGCGATCTACTACGAAAAAGCCATCCTCCAAAAGTCAGG
  GAGCGCCATTTTTCTGAAAGCACTTCTATTGACAATGCCCTGAGTCGACTGACCCTTGGG
  AATGAATTCTCTGTCAACAATGGGTACAGTCGAAGATTCAGATCTTTTTCTGAACTCCCC
  TCCTGTGATGGAAATGAAAGTTGGGCTTATCGCAGCGGGACAAAAACAGGTCCCAGGTCT
  GCAATATCTATATACAGACCTATCGACTATGGGATCTTTGGGAAAGAACAACAGTTAGCT
  TTCTTAGAAAATGTAAAGAGGTCACTTACACAAGGAAGATTATGGAAACCAAGTTTTCTT
  AAGAACCCTGGCTTCCTAAAAGATGATTTGAGGAACCCTCCCAACCCCTCAGAGTCATTA
  AGCTCAAATTCTCCCAGTAGTCAGGTGCCAGAAGATGGCTTATCTCCAAGTGAACCGCTT
  AATATCTATGAGGATGACCCAGTGGACTCAGATTGTGACACAGACACAACCACAGATGAT
  GAATACTACCTGGATGAAAATGACAAAGAGTCAGAACTG
  
• Restriction Sites: Please inquire
• ACCN: NM_001144763
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001144763.1, NP_001138235.1
• RefSeq Size: 10164 bp
• RefSeq ORF: 5742 bp
• Locus ID: 23086
• Cytogenetics: 11q22.3
• Gene Summary: The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein is thought to be involved in exosome secretion and intracellular vesicle trafficking. Reduced expression of this gene results in keratin filament defects. Mutations in this gene have been associated with some cases of epidermolysis bullosa, an inherited skin fragility disorder. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (4) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.