IL31RA (NM_139017) Human Untagged Clone

CAT#: SC318244

IL31RA (untagged)-Human interleukin 31 receptor A (IL31RA)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL31RA
• Synonyms: CRL; CRL3; GLM-R; GLMR; GPL; hGLM-R; IL-31RA; PLCA2; PRO21384; zcytoR17
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_139017, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGCATCAGGCAACTCAAGTTTTTCACCACGGCATGTGTCTGTGAATGTCCGCAAAACATTCTCTCTC
  CCCAGCCTTCATGTGTTAACCTGGGGATGATGTGGACCTGGGCACTGTGGATGCTCCCCTCACTCTGCAA
  ATTCAGCCTGGCAGCTCTGCCAGCTAAGCCTGAGAACATTTCCTGTGTCTACTACTATAGGAAAAATTTA
  ACCTGCACTTGGAGTCCAGGAAAGGAAACCAGTTATACCCAGTACACAGTTAAGAGAACTTACGCTTTTG
  GAGAAAAACATGATAATTGTACAACCAATAGTTCTACAAGTGAAAATCGTGCTTCGTGCTCTTTTTTCCT
  TCCAAGAATAACGATCCCAGATAATTATACCATTGAGGTGGAAGCTGAAAATGGAGATGGTGTAATTAAA
  TCTCATATGACATACTGGAGATTAGAGAACATAGCGAAAACTGAACCACCTAAGATTTTCCGTGTGAAAC
  CAGTTTTGGGCATCAAACGAATGATTCAAATTGAATGGATAAAGCCTGAGTTGGCGCCTGTTTCATCTGA
  TTTAAAATACACACTTCGATTCAGGACAGTCAACAGTACCAGCTGGATGGAAGTCAACTTCGCTAAGAAC
  CGTAAGGATAAAAACCAAACGTACAACCTCACGGGGCTGCAGCCTTTTACAGAATATGTCATAGCTCTGC
  GATGTGCGGTCAAGGAGTCAAAGTTCTGGAGTGACTGGAGCCAAGAAAAAATGGGAATGACTGAGGAAGA
  AGCTCCATGTGGCCTGGAACTGTGGAGAGTCCTGAAACCAGCTGAGGCGGATGGAAGAAGGCCAGTGCGG
  TTGTTATGGAAGAAGGCAAGAGGAGCCCCAGTCCTAGAGAAAACACTTGGCTACAACATATGGTACTATC
  CAGAAAGCAACACTAACCTCACAGAAACAATGAACACTACTAACCAGCAGCTTGAACTGCATCTGGGAGG
  CGAGAGCTTTTGGGTGTCTATGATTTCTTATAATTCTCTTGGGAAGTCTCCAGTGGCCACCCTGAGGATT
  CCAGCTATTCAAGAAAAATCATTTCAGTGCATTGAGGTCATGCAGGCCTGCGTTGCTGAGGACCAGCTAG
  TGGTGAAGTGGCAAAGCTCTGCTCTAGACGTGAACACTTGGATGATTGAATGGTTTCCGGATGTGGACTC
  AGAGCCCACCACCCTTTCCTGGGAATCTGTGTCTCAGGCCACGAACTGGACGATCCAGCAAGATAAATTA
  AAACCTTTCTGGTGCTATAACATCTCTGTGTATCCAATGTTGCATGACAAAGTTGGCGAGCCATATTCCA
  TCCAGGCTTATGCCAAAGAAGGCGTTCCATCAGAAGGTCCTGAGACCAAGGTGGAGAACATTGGCGTGAA
  GACGGTCACGATCACATGGAAAGAGATTCCCAAGAGTGAGAGAAAGGGTATCATCTGCAACTACACCATC
  TTTTACCAAGCTGAAGGTGGAAAAGGATTCTCCAAGACAGTCAATTCCAGCATCTTGCAGTACGGCCTGG
  AGTCCCTGAAACGAAAGACCTCTTACATTGTTCAGGTCATGGCCAGCACCAGTGCTGGGGGAACCAACGG
  GACCAGCATAAATTTCAAGACATTGTCATTCAGTGTCTTTGAGATTATCCTCATAACTTCTCTGATTGGT
  GGAGGCCTTCTTATTCTCATTATCCTGACAGTGGCATATGGTCTCAAAAAACCCAACAAATTGACTCATC
  TGTGTTGGCCCACCGTTCCCAACCCTGCTGAAAGTAGTATAGCCACATGGCATGGAGATGATTTCAAGGA
  TAAGCTAAACCTGAAGGAGTCTGATGACTCTGTGAACACAGAAGACAGGATCTTAAAACCATGTTCCACC
  CCCAGTGACAAGTTGGTGATTGACAAGTTGGTGGTGAACTTTGGGAATGTTCTGCAAGAAATTTTCACAG
  ATGAAGCCAGAACGGGTCAGGAAAACAATTTAGGAGGGGAAAAGAATGGGTATGTGACCTGCCCCTTCAG
  GCCTGATTGTCCCCTGGGGAAAAGTTTTGAGGAGCTCCCAGTTTCACCTGAGATTCCGCCCAGAAAATCC
  CAATACCTACGTTCGAGGATGCCAGAGGGGACCCGCCCAGAAGCCAAAGAGCAGCTTCTCTTTTCTGGTC
  AAAGTTTAGTACCAGATCATCTGTGTGAGGAAGGAGCCCCAAATCCATATTTGAAAAATTCAGTGACAGC
  CAGGGAATTTCTTGTGTCTGAAAAACTTCCAGAGCACACCAAGGGAGAAGTCTAA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_139017
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_139017.4, NP_620586.3
• RefSeq Size: 2393 bp
• RefSeq ORF: 2295 bp
• Locus ID: 133396
• UniProt ID: Q8NI17
• Cytogenetics: 5q11.2
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (1).