ZFYVE16 (NM_001105251) Human Untagged Clone

CAT#: SC317170

ZFYVE16 (untagged)-Human zinc finger, FYVE domain containing 16 (ZFYVE16), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZFYVE16
• Synonyms: PPP1R69
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001105251, the custom clone sequence may differ by one or more nucleotides
  ATGGACAGTTATTTTAAAGCAGCTGTCAGTGACTTGGACAAACTCCTTGATGATTTTGAA
  CAGAACCCAGATGAACAAGATTATCTCCAAGATGTACAAAATGCATATGATTCTAACCAC
  TGCTCAGTTTCTTCAGAGTTGGCTTCCTCACAGCGAACTTCATTGCTCCCAAAAGACCAA
  GAGTGCGTTAATAGTTGTGCCTCATCAGAAACAAGCTATGGAACAAATGAGAGTTCCCTG
  AATGAAAAAACACTCAAGGGACTTACTTCTATACAAAATGAAAAAAATGTAACAGGACTT
  GATCTTCTTTCTTCTGTGGATGGTGGTACTTCAGATGAAATCCAGCCGTTATATATGGGA
  CGATGTAGTAAACCTATCTGTGATCTGATAAGTGACATGGGTAACTTAGTTCATGCAACC
  AATAGTGAAGAAGATATTAAAAAATTATTGCCAGATGATTTTAAGTCTAATGCAGATTCC
  TTGATTGGATTGGATTTATCTTCAGTGTCAGATACTCCCTGTGTTTCTTCAACAGACCAT
  GATAGTGATACTGTCAGAGAACAACAGAATGATATCAGTTCTGAATTACAAAATAGAGAA
  ATCGGAGGAATCAAAGAATTGGGTATAAAAGTAGATACAACACTTTCAGATTCCTATAAT
  TACAGTGGAACAGAAAATTTAAAAGATAAAAAGATCTTTAATCAGTTAGAATCAATTGTT
  GATTTTAACATGTCATCTGCTTTGACTCGACAAAGTTCCAAAATGTTTCATGCCAAAGAC
  AAGCTACAACACAAGAGCCAGCCATGTGGATTACTAAAAGATGTTGGCTTAGTAAAAGAG
  GAAGTAGATGTGGCAGTCATAACTGCCGCAGAATGTTTAAAAGAAGAGGGCAAGACAAGT
  GCTTTGACCTGCAGCCTTCCGAAAAATGAAGATTTATGCTTAAATGATTCAAATTCAAGA
  GATGAAAATTTCAAATTACCTGACTTTTCCTTTCAGGAAGATAAGACTGTTATAAAACAA
  TCTGCACAAGAAGACTCAAAAAGTTTAGACCTTAAGGATAATGATGTAATCCAAGATTCC
  TCTTCAGCTTTACATGTTTCCAGTAAAGATGTGCCGTCCTCATTGTCCTGTCTTCCTGCG
  TCTGGGTCTATGTGTGGATCATTAATTGAAAGTAAAGCACGGGGTGATTTTTTACCTCAG
  CATGAACATAAAGATAATATACAAGATGCAGTGACTATACATGAAGAAATACAGAACAGT
  GTTGTTCTAGGTGGGGAACCATTCAAAGAGAATGATCTTTTGAAACAGGAAAAATGTAAA
  AGCATACTCCTTCAGTCATTAATTGAAGGGATGGAAGACAGAAAGATAGATCCTGACCAG
  ACAGTAATCAGAGCTGAGTCTTTGGATGGTGGTGACACCAGTTCTACAGTTGTAGAATCT
  CAAGAGGGGCTTTCTGGCACTCATGTCCCAGAGTCTTCTGATTGTTGTGAAGGTTTTATT
  AATACTTTTTCAAGCAATGATATGGATGGGCAAGACTTAGATTACTTTAATATTGATGAA
  GGCGCAAAAAGTGGCCCACTAATTAGTGATGCTGAACTTGATGCCTTTCTGACAGAACAG
  TATCTTCAGACCACTAACATAAAGTCTTTTGAAGAAAATGTAAATGACTCTAAATCGCAA
  ATGAATCAGATAGATATGAAAGGCTTAGATGATGGAAACATCAATAATATATATTTCAAT
  GCAGAAGCAGGAGCTATTGGGGAAAGTCATGGTATTAATATAATTTGTGAAACAGTTGAT
  AAACAAAATACAATAGAAAATGGCCTTTCTTTAGGAGAAAAAAGCACTATTCCAGTTCAA
  CAAGGGTTACCTACCAGTAAGTCTGAGATTACAAATCAATTATCAGTCTCTGATATTAAC
  AGTCAATCTGTTGGAGGGGCCAGACCTAAGCAATTGTTTAGCCTTCCATCAAGAACAAGG
  AGTTCAAAGGACCTGAATAAGCCAGATGTTCCAGATACAATAGAAAGTGAACCCAGCACA
  GCAGATACCGTTGTTCCAATCACTTGTGCTATAGATTCTACAGCTGATCCACAGGTTAGC
  TTCAACTCTAATTACATTGATATAGAAAGTAATTCTGAAGGTGGATCTAGTTTCGTAACT
  GCAAATGAAGATTCTGTACCTGAAAACACTTGCAAAGAAGGCTTGGTTTTGGGCCAGAAA
  CAGCCTACTTGGGTTCCTGATTCAGAAGCTCCAAACTGTATGAACTGCCAAGTCAAATTT
  ACTTTTACCAAACGGCGACACCATTGCCGAGCATGTGGGAAAGTATTTTGTGGTGTCTGT
  TGTAATAGGAAGTGTAAACTGCAATATCTAGAAAAGGAAGCAAGAGTATGTGTAGTCTGC
  TATGAAACTATTAGTAAAGCTCAGGCATTTGAAAGGATGATGAGTCCAACTGGTTCTAAT
  CTTAAGTCTAATCATTCTGATGAATGTACTACTGTCCAGCCTCCTCAGGAGAACCAAACA
  TCCAGTATACCTTCACCAGCAACTTTGCCAGTCTCAGCACTTAAACAACCAGGTGTTGAA
  GGACTATGTTCCAAAGAACAGAAGAGAGTATGGTTTGCAGATGGTATATTGCCCAATGGT
  GAAGTTGCAGATACAACAAAATTATCATCTGGAAGTAAAAGATGTTCTGAAGACTTTAGT
  CCTCTCTCACCTGATGTGCCTATGACAGTAAACACAGTGGATCATTCCCATTCTACTACA
  GTGGAAAAGCCAAACAATGAGACAGGAGATATTACAAGAAATGAGATAATTCAGAGTCCT
  ATTTCTCAGGTTCCATCAGTGGAAAAATTGTCTATGAACACAGGAAATGAGGGGTTACCT
  ACTTCTGGTTCATTTACACTAGATGATGATGTTTTTGCAGAAACTGAAGAACCATCTAGT
  CCTACTGGTGTCTTAGTTAACAGCAATTTACCTATTGCTAGTATTTCAGATTATAGGTTA
  CTGTGTGATATTAACAAGTATGTCTGCAATAAGATTAGTCTTCTACCTAATGATGAGGAC
  AGTTTGCCCCCACTTCTGGTTGCATCTGGAGAAAAGGGATCAGTGCCTGTAGTAGAAGAA
  CATCCATCTCATGAGCAGATCATTTTGCTTCTTGAAGGTGAAGGCTTTCATCCTGTTACA
  TTTGTCCTAAATGCTAATCTACTCGTGAATGTCAAATTCATATTTTATTCCTCAGACAAA
  TATTGGTACTTTTCAACCAATGGATTGCATGGCTTGGGACAGGCAGAAATTATTATTCTA
  TTGTTATGTTTGCCAAATGAAGATACTATTCCTAAGGACATCTTCAGACTATTTATCACC
  ATATATAAGGATGCTCTAAAAGGAAAATACATAGAAAACTTGGACAATATTACCTTTACT
  GAGAGTTTTCTCAGTAGCAAGGATCACGGAGGATTCCTGTTTATTACACCTACTTTTCAG
  AAACTTGATGATCTCTCATTACCAAGTAATCCTTTTCTTTGTGGAATTCTTATCCAGAAG
  CTTGAGATTCCCTGGGCAAAGGTTTTTCCTATGCGTTTAATGTTGAGATTGGGTGCAGAA
  TATAAAGCATATCCTGCTCCTCTAACAAGCATCAGAGGCCGAAAACCTCTTTTTGGAGAA
  ATAGGACACACTATTATGAACTTACTTGTTGACCTTCGAAATTACCAGTATACCTTGCAT
  AATATAGATCAACTGTTGATTCATATGGAAATGGGAAAAAGCTGCATAAAAATACCACGG
  AAAAAGTACAGTGATGTAATGAAAGTACTAAATTCTTCCAATGAGCATGTCATTAGCATT
  GGAGCAAGTTTCAGTACAGAAGCAGATTCTCATCTAGTCTGTATACAGAATGATGGAATT
  TATGAAACACAGGCCAACAGTGCCACTGGCCATCCTAGAAAAGTGACAGGTGCAAGTTTT
  GTGGTATTCAATGGAGCTCTAAAAACATCTTCAGGATTTCTTGCTAAGTCCAGCATAGTT
  GAAGATGGCTTAATGGTACAAATAACTCCAGAGACCATGAATGGCTTGCGGCTAGCTTTA
  CGAGAACAGAAAGACTTTAAAATTACATGTGGGAAAGTTGATGCAGTAGACCTGAGAGAA
  TACGTGGATATCTGCTGGGTAGATGCTGAAGAAAAAGGAAACAAAGGAGTTATCAGTTCA
  GTGGATGGAATATCATTACAAGGATTTCCAAGTGAAAAAATAAAACTGGAAGCAGATTTT
  GAAACCGATGAGAAGATTGTAAAATGTACCGAGGTGTTCTACTTTCTAAAGGACCAGGAT
  TTATCTATTTTATCAACTTCTTATCAGTTTGCAAAAGAAATAGCCATGGCTTGTAGTGCT
  GCGCTGTGCCCTCACCTGAAAACTCTAAAAAGTAATGGGATGAATAAAATTGGACTCAGA
  GTTTCCATTGACACTGATATGGTTGAATTTCAGGCAGGATCTGAAGGCCAACTTCTGCCT
  CAGCATTATCTAAATGATCTTGATAGTGCTCTGATACCTGTGATCCATGGTGGGACCTCC
  AACTCTAGTTTACCATTAGAAATAGAATTAGTGTTTTTCATTATAGAACATCTTTTT
  
• Restriction Sites: Please inquire
• ACCN: NM_001105251
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001105251.1, NP_001098721.1
• RefSeq Size: 7224 bp
• RefSeq ORF: 4620 bp
• Locus ID: 9765
• Cytogenetics: 5q14.1
• Protein Pathways: TGF-beta signaling pathway
• Gene Summary: This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 5 encode the same protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.