Hdac7 (NM_001204276) Mouse Tagged ORF Clone
CAT#: MR231412
- TrueORF®
Hdac7 (myc-DDK-tagged) - Mouse histone deacetylase 7 (Hdac7), transcript variant 2
"NM_001204276" in other vectors (1)
Interest in protein/lysate? Submit request here!
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Hdac7 |
Synonyms | 5830434K02Rik; HD7; HD7a; Hdac7a; mFLJ00062 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR231412 representing NM_001204276
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACCTGCGGGTGGGCCAGCGGCCCACGGTGGAGCCCCCACCAGAGCCTGCGCTGCTGACCCTGCAAC ACCCCCAACGCCTGCACCGCCATCTCTTCCTGGCAGGCTTACACCAGCAACAGCGCTCAGCCGAGCCCAT GAGGCTCTCCATGGACCCACCAATGCCGGAGCTGCAGGGGGGACAGCAGGAGCAAGAACTTCGGCAACTT CTCAATAAAGACAAGAGCAAGCGAAGTGCCGTAGCCAGCAGTGTGGTCAAGCAGAAGCTGGCTGAAGTGA TCCTGAAGAAACAGCAGGCAGCCCTTGAGAGAACAGTCCATCCCAGCAGCCCCAGTATTCCCTACAGAAC TCTTGAGCCCTTGGACACAGAGGGTGCTGCCCGCTCCGTGCTTAGCAGCTTCCTGCCTCCTGTTCCCAGC CTGCCCACTGAACCCCCGGAACACTTTCCCTTGCGTAAAACAGTGTCTGAACCCAACCTGAAGTTGCGCT ACAAACCCAAGAAATCCCTGGAGAGACGCAAGAATCCCCTGCTCAGGAAGGAGAGTGCCCCGCCCAGCCT TCGGAGGAGGCCTGCCGAGACCCTTGGAGATTCCTCCCCCAGTAGTAGCAGCACACCCGCGTCAGGGTGC AGCTCCCCTAATGACAGCGAGCATGGCCCTAACCCTGCCCTAGGCTCAGAGGCGCTCTTGGGCCAGCGGC TGCGGCTGCAGGAGACTTCTCTGGCCCCGTTCGCTTTGCCGACAGTGTCCTTGCTGCCCGCAATCACACT GGGGCTGCCTGCCCCTGCCAGGGCTGATGGTGACCGCAGGACCCATTCAACTTTAGGCCCTCGGGGTCCT GTACTGGGGAACCCCCATGCTCCCCTCTTCCTGCACCACGGTCTGGAGCCAGAGGCTGGGGGCACCTTAC CCTCTCGCCTGCAACCCATTCTCCTGCTGGACCCCTCAGTCTCTCATGCCCCACTGTGGACTGTGCCTGG CCTTGGGCCCTTGCCCTTCCACTTTGCCCAGCCCTTACTGACCACCGAGCGGCTCTCTGGGTCAGGCCTC CATCGACCACTTAACCGGACCCGCTCAGAGCCCCTGCCCCCCAGCGCCACAGCCTCCCCTCTGCTGGCCC CCCTGCAGCCCCGCCAGGATCGGCTCAAACCTCACGTCCAGCTGATCAAGAGGCCTGCCAAGCCCAGTGA GAAGCCCCGACTGCGACAGATACCCTCGGCTGAGGACCTAGAGACAGATGGTGGGGGAGTGGGACCTATG GCGAATGATGGCCTGGAACATAGGGAGTCAGGCCGTGGGCCTCCTGAGGGCAGAGGCTCCATTTCTCTGC AGCAGCATCAACAGGTGCCACCCTGGGAGCAGCAGCATCTAGCCGGGCGGCTCTCTCAGGGAAGCCCCGG GGACTCCGTGCTGATACCTCTGGCCCAGGTTGGACACCGGCCCCTGTCCAGAACCCAGTCTTCCCCAGCA GCACCTGTCTCCCTGCTGAGCCCAGAGCCCACCTGTCAGACCCAAGTCCTCAACAGCTCAGAGACACCTG CTACAGGGCTGGTCTATGACTCGGTGATGCTGAAACACCAATGTTCCTGTGGAGACAACAGCAAGCATCC CGAGCATGCAGGCCGCATCCAGAGCATCTGGTCCCGGCTGCAGGAACGGGGTCTCCGCAGCCAGTGTGAG TGTCTCCGAGGCCGAAAGGCTTCCCTAGAGGAGCTGCAGTCAGTCCACTCTGAACGGCACGTGCTCCTCT ACGGCACGAACCCACTCAGCCGCCTCAAACTGGATAACGGGAAGCTTACAGGACTCCTGGCACAGCGGAC GTTTGTGATGCTACCCTGTGGCGGGGTTGGGGTCGATACTGACACCATCTGGAACGAGCTGCATTCCTCC AATGCAGCCCGCTGGGCTGCGGGCAGTGTCACCGACCTTGCCTTCAAAGTAGCTTCCCGAGAGCTGAAGA ATGGCTTTGCTGTGGTGCGACCCCCGGGACACCATGCAGATCATTCTACAGCCATGGGCTTCTGCTTCTT CAACTCCGTGGCCATCGCCTGCCGACAGCTACAGCAACACGGCAAAGCCAGCAAGATCCTCATTGTTGAC TGGGATGTTCACCATGGCAACGGCACACAGCAGACTTTCTACCAGGACCCCAGTGTGCTCTACATTTCCC TTCATCGCCATGACGACGGCAACTTCTTCCCAGGCAGTGGGGCCGTGGATGAGGTGGGAACTGGCAGTGG CGAGGGCTTCAATGTCAACGTGGCTTGGGCTGGGGGCTTGGATCCACCCATGGGGGATCCTGAGTACCTG GCTGCTTTCAGGATAGTGGTGATGCCCATTGCCCGAGAGTTTGCTCCAGACCTGGTCCTGGTGTCTGCTG GGTTTGATGCTGCGGAGGGTCACCCAGCCCCGCTGGGTGGCTACCATGTTTCTGCCAAATGTTTTGGGTA CATGACGCAGCAGTTGATGAACTTGGCAGGAGGCGCCGTGGTGTTGGCCTTAGAGGGTGGACATGACCTC ACGGCCATCTGTGATGCCTCGGAGGCCTGTGTAGCTGCTCTTCTGGGCAACAAGGTGGACCCCCTTTCAG AAGAAAGCTGGAAACAGAAACCCAACCTCAGTGCCATCCGCTCGCTGGAAGCTGTGGTCAGGGTGCACAG GAAATACTGGGGCTGCATGCAGCGCTTGGCCTCCTGTCCAGACTCCTGGCTACCCAGAGTGCCGGGAGCT GATGCAGAAGTGGAAGCCGTGACCGCGCTGGCATCCCTTTCTGTGGGCATCCTGGCTGAAGACAGGCCCT CGGAGCGGCTGGTGGAAGAGGAAGAACCCATGAACCTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR231412 representing NM_001204276
Red=Cloning site Green=Tags(s) MDLRVGQRPTVEPPPEPALLTLQHPQRLHRHLFLAGLHQQQRSAEPMRLSMDPPMPELQGGQQEQELRQL LNKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPSSPSIPYRTLEPLDTEGAARSVLSSFLPPVPS LPTEPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLGDSSPSSSSTPASGC SSPNDSEHGPNPALGSEALLGQRLRLQETSLAPFALPTVSLLPAITLGLPAPARADGDRRTHSTLGPRGP VLGNPHAPLFLHHGLEPEAGGTLPSRLQPILLLDPSVSHAPLWTVPGLGPLPFHFAQPLLTTERLSGSGL HRPLNRTRSEPLPPSATASPLLAPLQPRQDRLKPHVQLIKRPAKPSEKPRLRQIPSAEDLETDGGGVGPM ANDGLEHRESGRGPPEGRGSISLQQHQQVPPWEQQHLAGRLSQGSPGDSVLIPLAQVGHRPLSRTQSSPA APVSLLSPEPTCQTQVLNSSETPATGLVYDSVMLKHQCSCGDNSKHPEHAGRIQSIWSRLQERGLRSQCE CLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLTGLLAQRTFVMLPCGGVGVDTDTIWNELHSS NAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQHGKASKILIVD WDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGTGSGEGFNVNVAWAGGLDPPMGDPEYL AAFRIVVMPIAREFAPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDL TAICDASEACVAALLGNKVDPLSEESWKQKPNLSAIRSLEAVVRVHRKYWGCMQRLASCPDSWLPRVPGA DAEVEAVTALASLSVGILAEDRPSERLVEEEEPMNL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_001204276 |
ORF Size | 2838 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001204276.1, NP_001191205.1 |
RefSeq Size | 4387 bp |
RefSeq ORF | 2841 bp |
Locus ID | 56233 |
UniProt ID | Q8C2B3 |
Cytogenetics | 15 F1 |
MW | 102.7 kDa |
Gene Summary | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Positively regulates the transcriptional repressor activity of FOXP3 (By similarity). Serves as a corepressor of RARA, causing its deacetylation and inhibition of RARE DNA element binding (By similarity). In association with RARA, plays a role in the repression of microRNA-10a and thereby in the inflammatory response (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC229201 | Hdac7 (untagged) - Mouse histone deacetylase 7 (Hdac7), transcript variant 2 |
USD 954.00 |
{0} Product Review(s)
Be the first one to submit a review