Cirbp (NM_007705) Mouse Untagged Clone

CAT#: MC203526

Cirbp (untagged) - Mouse cold inducible RNA binding protein (Cirbp), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cirbp
• Synonyms: Cirp; R74941
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC075699
  TAGGAAGCTTGGGTGTGTGTGGCGCGCTGTCTTCCCGCTCGCGTCAGGGACCTGCCCGACTCAGCGGCTG CCATGGCATCAGATGAAGGCAAGCTTTTCGTGGGAGGACTCAGCTTCGACACCAACGAGCAGGCGCTGGA GCAGGTCTTCTCCAAGTATGGGCAGATCTCCGAAGTGGTGGTGGTAAAGGACAGGGAGACCCAGCGATCC CGAGGCTTTGGGTTTGTCACCTTTGAAAATATCGATGACGCTAAGGACGCCATGATGGCTATGAATGGGA AGTCTGTGGACGGGCGGCAGATCAGAGTTGACCAGGCTGGCAAGTCTTCTGACAACCGGTCCCGAGGATA CCGGGGTGGCTCTGCTGGAGGCCGGGGCTTTTTCCGTGGGGGACGAAGCCGGGGCCGAGGGTTCTCCAGA GGAGGAGGAGACCGGGGCTATGGAGGTGGCCGCTTTGAGTCCCGGAGTGGGGGTTATGGAGGCTCCAGAG ACTACTATGCCAGCCGGAGTCAGGGTGGCAGCTATGGTTATCGGAGCTCGGGAGGGTCCTACAGAGACAG CTATGACAGTTATGCTACACACAACGAGTAAAAGCCCTCCGCGTCCAGATCGTCCTTCCATGGCTGTAAT TAAGATGGGGGAGCTTCGCTGATCGTTGTGTAGTGAGCACCTTGTTCCCACTTTTGTAGTCCTTTCCGTT CTGACCCGTCAGCAGCCTGCTTCTGACCCAAGATGGCCTCGTGACTAGACCTGTTTTTAAGGAAGCGCTG TCTGTTTTTAAGTATTCTTAAAAACGTTTTGGAAAGCACTTCAGATTTTACTGTTTACCATGAGCCATGG GTTTTTGTTTTTTCTAAATTGTCGGGTTGTGTGGGTTTTGGTTACTCGTTTTTGTTTTTTCAGGTTTTTT GGTTGTGGCTTTTCTTTTTTTTTCTTTTTTTGTGTGGTCGCCCCTGAAGTCTGGCGCCCCACCCCTCCTG AGATGGAATGGACTCGATTTGAGCAAGCCATGGCCCTCCAGCTCCCCAGCCCGGCTGCGGAGTTGCAGCA GGTCCTGCCCATCGGGCACATGTCTCAAGCCCATGGGGAGCATAGCAGTCCGGGAGGCTGTGGAAATGTT TATTTATATTGTCCTTTTTTACCGAAGACATGCATACTCCATCGATGTTGTATTCACAGTGGCTGAGGAA TTCTTGTACGCAGTTTCTTTGGCTTCACGAAGCCGATTAAAAGACCGTGTGAAATGAAAAAAAAAAAAAA AAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_007705
• Insert Size: 519 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC075699, AAH75699
• RefSeq Size: 1276 bp
• RefSeq ORF: 519 bp
• Locus ID: 12696
• UniProt ID: P60824
• Cytogenetics: 10 39.72 cM
• Gene Summary: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN.[UniProtKB/Swiss-Prot Function]