Sike1 (NM_025679) Mouse Untagged Clone

CAT#: MC200385

Sike1 (untagged) - Mouse suppressor of IKBKE 1 (Sike1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sike1
• Synonyms: 2810005O12Rik; 5730470L24Rik; AI450236; AI839862; Sike; Sikeb
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004090 sequence for NM_025679
  CGGACGCGTGGGGGCCGGGTAAGGTCTGAGCGAAGCGCCTAGGCTAGCGGGCCCGGCGCGCCTCCTCGGC CACTATGAGCTGCACGATCGAGAAGATCTTGACGGACGCCAAGACGCTGCTGGAGCGGCTGCGCGAGCAC GATGCGGCGGCCGAGTCGCTGGTGGACCAGTCGGCTGCGCTGCACCGGCGGGTGGCGGCGATGCGGGAGG CGGGCGCCGTGTTACCCGAGCAGTATCAAGAGGATGCATCCGACGTGAAGGACATGTCTAAATATAAACC TCACATTCTGCTGTCTCAAGAGAATACCCAGATTAGAGACTTACAGCAGGAAAACAGAGAACTGTGGGTT TCCTTGGAGGAGCACCAGGATGCGTTGGAACTGATCATGAGCAAGTACCGGAAACAGATGTTACAGTTAA TGGTCGCTAAGAAAGCCGTGGATGCCGAACCAGTTCTGAAAGCTCACCAGTCTCACTCTGCAGAGATTGA AAGTCAGATCGATAGAATCTGTGAAATGGGAGCAGTGATGCGGAGAGCTGTTCAGGTGGACGATAACCAA TTCTGTAAGGTTCAGGAGAGACTAGCTCAGCTGGAGCTTGAAAATAAGGAACTTCGAGAGTTACTGTCCA TCAGCAGTGAATCTCTGCAGGTTGGAAAAGAAAGCTCTGTGGCTCCTGCCTCTCAGACCATCAAGTAACT GGACTTCCGAAGGCTGGCTACAGCTTGCCCGTCAGAGCGAGAAGCCGTGCCCTCCTCTCCTGCCGTGTCC AAGAGTCCTGCCGCAGACTTGACTTAGTGTTGGGTAGAGGTATGGGGTGGCAGTTTAGAATTGCCACTTG GTATTCATTGTCCACTAACTAGTTTGGGGTGTACTAGTGAAACTAGACAAGTCCCCCATTGCTGGGACAG AGATGACATTTGTCACTCTAGTCCGGAATCTCTATAAACTGTTACCTGCAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_025679
• Insert Size: 624 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004090, AAH04090
• RefSeq Size: 992 bp
• RefSeq ORF: 624 bp
• Locus ID: 66641
• UniProt ID: Q9CPR7
• Cytogenetics: 3 F2.2
• Gene Summary: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).[UniProtKB/Swiss-Prot Function]