TANK (NM_004180) Human 3' UTR Clone

CAT#: SC208531

3' UTR clone of TRAF family member-associated NFKB activator (TANK) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: TANK
• Synonyms: I-TRAF; ITRAF; TRAF2
• ACCN: NM_004180
• Insert Size: 742 bp
• Sequence Data:
  Insert Sequence

  >SC208531 3’UTR clone of NM_004180
  The sequence shown below is from the reference sequence of NM_004180. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  CTTAATTCACACTTCAATGGAGAGACTTAAGACACATTTGAAAACAGACATATCAAGTTCTATGTGATG
  ATTTTGGGTTTTTAATACTATAAATACTTGATTGTAAACTAAATTCAAGATCATTTATAGGAAAATCTA
  GTTTCACAGCTATTTGAATTTTTTTCTGGATTTACTATATAACTCTTATTTTTTAAAAGATCATTCTGT
  TCTTTCAAGGAGAAATAAGCCTAAAAGAAGAAAAACAAAAAAAATTCTGTATAAAACTGTAATCCTTTG
  TATTCATGTTTACAGTGCTATTACTATAATTCAAAATTATGTATGTGACTTAGAGTTATATAATCATAA
  TTTATGTTTATTTCAAATATCTAAGTTTATTGCTTGGATTTCTAGTGAGAGCTGTTGAATTTGGTGATG
  TCAAATGTTTCTAGGGTTTTTTTAGTTTGTTTTTATTGAAAAATTTAATTATTTATGCTATAGGTGATA
  TTCTCTTTGAATAAACCTATAATAGAAAATAGCAGACAACATAAACATCTTTGTAAATATCAAACCTAA
  TACATTTCTTGTCCAGTGATAAAACAACTGGTAGAATTATTTAAACACTTTAGATTTTTAAATAATATA
  CATGGCTTTAATTTTTACTGTGTGTATAGCTACATGATGAAATTAATTAAATATTAAGAGGTACTTATG
  TTGTGATCATTTGTATGTCCTTTGTTCCTGAGTAAAAAAAAAAAAAAAAAAA
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_004180.3
• Summary: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
• Locus ID: 10010
• MW: 29.8