Progesterone Receptor (PGR) Mouse Monoclonal Antibody [Clone ID: UMAB136]
CAT#: UM800037CF
Carrier-free (BSA/glycerol-free) PR (PgR) mouse monoclonal antibody,clone UMAB136
Formulation: Standard
Frequently bought together (1)
Other products for "Progesterone Receptor"
Specifications
Product Data | |
Clone Name | UMAB136 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:200 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-298 of human PGR (NP_000917) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | progesterone receptor |
Database Link | |
Background | This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Jan 2011] |
Synonyms | NR3C3; PR |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | Oocyte meiosis, Progesterone-mediated oocyte maturation |
Documents
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