Orexin (HCRT) Rabbit Polyclonal Antibody

CAT#: TA890065

Rabbit polyclonal anti-HCRT Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Cat# PS100001, Left lane) or pCMV6-ENTRY HCRT (Cat# RC217956, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HCRT antibody (Cat# TA890065). Positive lysates LY419884 (100ug) and LC419884 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human HCRT
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 2.52mg/ml
• Purification: Purified from the immunized serum by affinity chromatography (Protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 13.2 kDa
• Gene Name: hypocretin (orexin) neuropeptide precursor
• Database Link:
  NP_001515
  Entrez Gene 25723 RatEntrez Gene 3060 Human
  UniProt ID O43612
• Background: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]
• Synonyms: NRCLP1; OX; PPOX

Reference Data

• Protein Families: Druggable Genome, Transmembrane