Activin Receptor Type IIA (ACVR2A) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1F2]
CAT#: TA807404BM
ACVR2A mouse monoclonal antibody,clone OTI1F2, HRP conjugated
Conjugation: Unconjugated Biotin
Specifications
Product Data | |
Clone Name | OTI1F2 |
Applications | IHC, WB |
Recommended Dilution | WB 1:500, IHC 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 214-513 of human ACVR2A(NP_001607) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 56 kDa |
Gene Name | activin A receptor type 2A |
Database Link | |
Background | This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013] |
Synonyms | ACTRII; ACVR2 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF807404 | Carrier-free (BSA/glycerol-free) ACVR2A mouse monoclonal antibody,clone OTI1F2 |
USD 600.00 |
|
TA807404 | ACVR2A mouse monoclonal antibody,clone OTI1F2 |
USD 447.00 |
|
TA807404AM | ACVR2A mouse monoclonal antibody,clone OTI1F2, Biotinylated |
USD 509.00 |
|
TA807404S | ACVR2A mouse monoclonal antibody,clone OTI1F2 |
USD 200.00 |
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