Caspase 4 (CASP4) Mouse Monoclonal Antibody [Clone ID: OTI4A2]
Specifications
Product Data | |
Clone Name | OTI4A2 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 81-270 of human CASP4 (NP_150649) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 36.5 kDa |
Gene Name | caspase 4 |
Database Link | |
Background | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Synonyms | ICE(rel)II; ICEREL-II; ICH-2; Mih1; Mih1/TX; TX |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF805590 | Carrier-free (BSA/glycerol-free) CASP4 mouse monoclonal antibody, clone OTI4A2 (formerly 4A2) |
USD 600.00 |
|
TA805590 | CASP4 mouse monoclonal antibody, clone OTI4A2 (formerly 4A2) |
USD 447.00 |
|
TA805590AM | CASP4 mouse monoclonal antibody, clone OTI4A2 (formerly 4A2), Biotinylated |
USD 509.00 |
|
TA805590BM | CASP4 mouse monoclonal antibody, clone OTI4A2 (formerly 4A2), HRP conjugated |
USD 509.00 |
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