MRTFA Mouse Monoclonal Antibody [Clone ID: OTI4D10]
Specifications
Product Data | |
Clone Name | OTI4D10 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 165-397 of human MKL1 (NP_065882) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | megakaryoblastic leukemia (translocation) 1 |
Database Link | |
Background | The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
Synonyms | BSAC; MAL; MRTF-A |
Reference Data | |
Protein Families | Transcription Factors |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA805136 | MKL1 mouse monoclonal antibody, clone OTI4D10 (formerly 4D10) |
USD 224.00 |
|
TA805136AM | MKL1 mouse monoclonal antibody, clone OTI4D10 (formerly 4D10), Biotinylated |
USD 509.00 |
|
TA805136BM | MKL1 mouse monoclonal antibody, clone OTI4D10 (formerly 4D10), HRP conjugated |
USD 509.00 |
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