gamma C Crystallin (CRYGC) Mouse Monoclonal Antibody [Clone ID: OTI1E3]
CAT#: TA505773
CRYGC (Gamma C Crystallin) mouse monoclonal antibody, clone OTI1E3 (formerly 1E3)
Size: 30 ul
Formulation: Carrier-Free
USD 867.00
Specifications
Product Data | |
Clone Name | OTI1E3 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CRYGC (NP_066269) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 20.7 kDa |
Gene Name | crystallin gamma C |
Database Link | |
Background | Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008] |
Synonyms | CCL; CRYG3; CTRCT2 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF505773 | Carrier-free (BSA/glycerol-free) CRYGC mouse monoclonal antibody, clone OTI1E3 (formerly 1E3) |
USD 600.00 |
|
TA505773AM | CRYGC mouse monoclonal antibody,clone 1E3, Biotinylated |
USD 509.00 |
|
TA505773BM | CRYGC mouse monoclonal antibody,clone 1E3, HRP conjugated |
USD 509.00 |
|
TA505773S | CRYGC (Gamma C Crystallin) mouse monoclonal antibody, clone OTI1E3 (formerly 1E3) |
USD 200.00 |
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