BCL10 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4A8]
CAT#: TA501237AM
BCL10 mouse monoclonal antibody, clone 4A8, Biotinylated
Conjugation: Unconjugated HRP PE
Specifications
Product Data | |
Clone Name | OTI4A8 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 26.1 kDa |
Gene Name | BCL10 immune signaling adaptor |
Database Link | |
Background | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
Synonyms | c-E10; CARMEN; CIPER; CLAP; IMD37; mE10 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | B cell receptor signaling pathway, T cell receptor signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF501237 | Carrier-free (BSA/glycerol-free) BCL10 mouse monoclonal antibody, clone OTI4A8 (formerly 4A8) |
USD 600.00 |
|
TA400004 | Anti-BCL10 mouse mAb, clone OTI4A8, PE conjugated |
USD 495.00 |
|
TA501237 | Anti-BCL10 mouse monoclonal antibody, clone OTI4A8 (formerly 4A8) |
USD 224.00 |
|
TA501237BM | BCL10 mouse monoclonal antibody, clone 4A8, HRP conjugated |
USD 509.00 |
|
TA501237S | Anti-BCL10 mouse monoclonal antibody, clone OTI4A8 (formerly 4A8) |
USD 200.00 |
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