CD59 Rabbit Polyclonal Antibody
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Other products for "CD59"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:1000~1:2000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CD59. |
Specificity | CD59 polyclonal antibody detects endogenous levels of CD59 protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Stability | 1 year |
Predicted Protein Size | ~17 kDa |
Gene Name | CD59 molecule |
Database Link | |
Background | Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
Synonyms | 1F5 antigen; 20 kDa homologous restriction factor; CD59; CD59 glycoprotein; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MACIF; MEM43 antigen; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIRL; Protectin |
Note | For research use only, not for use in diagnostic procedure. |
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