H2AC8 Rabbit Polyclonal Antibody

CAT#: TA384362

Histone H2A Rabbit polyclonal Antibody

Product Images

Western blot analysis of Histone H2A.Z in(1)Neuro2a lysates;(2)HeLa lysates using Histone H2A antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human kidney using Histone H2A.Z antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Histone H2A.Z
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 13kDa
• Gene Name: histone cluster 1, H2ae
• Database Link:
  Entrez Gene 3012 Human
  UniProt ID P04908
• Background: Swiss-Prot Acc.P04908.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
• Synonyms: H2A.1; H2A.2; H2A/a; H2A/m; H2AFA; H2AFM