FES Rabbit Monoclonal Antibody [Clone ID: R02-2F6]

CAT#: TA384216

FES Rabbit monoclonal Antibody

Product Images

Western blot detection of FES in Raji cell lysates using FES Rabbit mAb(1:1000 diluted).Predicted band size:94KDa.Observed band size:94KDa.

Specifications

Product Data

• Clone Name: R02-2F6
• Applications: WB
• Recommended Dilution: WB: 1/1000-1/5000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human FES
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 94 kDa; Observed MW: 94 kDa
• Gene Name: FES proto-oncogene, tyrosine kinase
• Database Link:
  Entrez Gene 2242 Human
  UniProt ID P07332
• Background: Swiss-Prot Acc.P07332.Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.
• Synonyms: C-Fes; FPS