FES Rabbit Monoclonal Antibody [Clone ID: R02-2F6]
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Other products for "FES"
Specifications
Product Data | |
Clone Name | R02-2F6 |
Applications | WB |
Recommended Dilution | WB: 1/1000-1/5000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human FES |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | Calculated MW: 94 kDa; Observed MW: 94 kDa |
Gene Name | FES proto-oncogene, tyrosine kinase |
Database Link | |
Background | Swiss-Prot Acc.P07332.Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28. |
Synonyms | C-Fes; FPS |
Reference Data |
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