GCKR Rabbit Polyclonal Antibody

CAT#: TA350012

Rabbit Polyclonal Anti-GCKR Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: Human placenta tissue mouse liver tissue Primary antibody: TA350012 (GCKR Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA350012 (GCKR Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA350012 (GCKR Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350012 (GCKR Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350012 (GCKR Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human placenta and mouse liver tissue
  IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human GCKR
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: glucokinase (hexokinase 4) regulator
• Database Link:
  NP_001477
  Entrez Gene 25658 RatEntrez Gene 231103 MouseEntrez Gene 2646 Human
  UniProt ID Q14397
• Background: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
• Synonyms: FGQTL5; GKRP