Desmin (DES) Rabbit Polyclonal Antibody

CAT#: TA347369

Rabbit Polyclonal Anti-Desmin Antibody

Product Images

Western blot analysis on HeLa cell lysate using Desmin Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Desmin Antibody: A synthesized peptide derived from human Desmin
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: desmin
• Database Link:
  NP_001918
  Entrez Gene 13346 MouseEntrez Gene 64362 RatEntrez Gene 1674 Human
  UniProt ID P17661
• Background: desmin a class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
• Synonyms: CSM1; CSM2; LGMD2R
• Note: Desmin antibody detects endogenous levels of total Desmin

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)