TCF3 / E2A (TCF3) Rabbit Polyclonal Antibody

CAT#: TA330898

Rabbit Polyclonal Anti-TCF3 Antibody

Product Images

Host: Rabbit; Target Name: TCF3; Sample Tissue: 786-0 Whole Cell lysates; Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-TCF3 antibody is: synthetic peptide directed towards the N-terminal region of Human TCF3. Synthetic peptide located within the following region: EDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGG
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 71 kDa
• Gene Name: transcription factor 3
• Database Link:
  NP_003191
  Entrez Gene 21423 MouseEntrez Gene 6929 Human
  UniProt ID P15923
• Background: TCF3 is a transcriptional regulator. It is involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. It binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.
• Synonyms: AGM8; bHLHb21; E2A; E47; ITF1; TCF-3; VDIR
• Note: Human: 100%; Dog: 86%; Mouse: 86%; Horse: 85%; Rat: 79%

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors