TIAM2 Goat Polyclonal Antibody

CAT#: TA329680

Goat Anti-TIAM2 Polyclonal Antibody

Product Images

TA329680 (5ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 5-10ug/ml
• Reactivities: Human (Expected from sequence similarity: Mouse, Dog)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence TLQGSKNHSNT-C, from the N Terminus of the protein sequence according to NP_036586.2
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: T-cell lymphoma invasion and metastasis 2
• Database Link:
  NP_001010927
  Entrez Gene 24001 MouseEntrez Gene 484045 DogEntrez Gene 26230 Human
  UniProt ID Q8IVF5
• Background: This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
• Synonyms: STEF; TIAM-2
• Note: IHC: In paraffin embedded Human Testis shows cytoskeletal staining in interstitial (Leydig) cells.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Chemokine signaling pathway, Regulation of actin cytoskeleton