NTAL (LAT2) Rabbit Polyclonal Antibody

CAT#: TA322392

Anti-LAT2 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322392 (LAT2 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322392 (LAT2 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 27-243 amino acids of human linker for activation of T cells family, member 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: linker for activation of T-cells family member 2
• Database Link:
  NP_054865
  Entrez Gene 7462 Human
  UniProt ID Q9GZY6
• Background: This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome; a multisystem developmental disorder. This gene consists of at least 14 exons; and its alternative splicing generates 3 transcript variants; all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
• Synonyms: HSPC046; LAB; NTAL; WBSCR5; WBSCR15; WSCR5

Reference Data

• Protein Families: Transmembrane