Estrogen Receptor 1 (ESR1) Rabbit Polyclonal Antibody
Frequently bought together (3)
Transient overexpression lysate of estrogen receptor 1 (ESR1), transcript variant 1
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Recombinant protein of human estrogen receptor 1 (ESR1), transcript variant 1, 20 µg
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Other products for "Estrogen Receptor 1"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 100-300 Positive control: Human brain Predicted cell location: Cytoplasm, Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 247-261 amino acids of Human estrogen receptor 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | estrogen receptor 1 |
Database Link | |
Background | This gene encodes an estrogen receptor; a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding; and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function; but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer; endometrial cancer; and osteoporosis. Alternative splicing results in several transcript variants; which differ in their 5' UTRs and use different promoters. |
Synonyms | ER; Era; ESR; ESRA; ESTRR; NR3A1 |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Documents
Product Manuals |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.