GRAP Goat Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human GRB2-related adaptor protein (GRAP), 20 µg
USD 867.00
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1:32,000. WB: 0.3-1µg/ml. |
Reactivities | Human (Expected from sequence similarity: Mouse, Rat, Cow) |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-GFFPRSYVQPVHL, from the C Terminus of the protein sequence according to NP_006604.1. |
Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | GRB2-related adaptor protein |
Database Link | |
Background | This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. COMPLETENESS: complete on the 3' end. |
Synonyms | MGC64880 |
Reference Data |
Documents
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