IP10 (CXCL10) Mouse Monoclonal Antibody [Clone ID: 4D5]

CAT#: SM1323P

IP10 (CXCL10) mouse monoclonal antibody, clone 4D5, Purified

Specifications

Product Data

• Clone Name: 4D5
• Applications: ELISA, WB
• Recommended Dilution: ELISA: 1-2 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human IP-10. Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3X63-AgP-653 myeloma cell line.
• Specificity: This antibody recognises both natural and recombinant IP-10, also known as CXCL10.
• Formulation: PBS, pH7.4 containing 0.09% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: C-X-C motif chemokine ligand 10
• Database Link:
  Entrez Gene 3627 Human
  UniProt ID P02778
• Background: Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.
• Synonyms: C-X-C motif chemokine 10, Small-inducible cytokine B10, Gamma-IP10, INP10, SCYB10