Calcitonin (CALCA) Guinea Pig Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | Immunofluorescence. Immunohistochemistry on Paraffin and Frozen Sections. Working Dilutions: 1/1000-1/1200 for Immunofluorescence microscopy with overnight incubation at 2-8°C. |
Reactivities | Human, Rat |
Host | Guinea Pig |
Clonality | Polyclonal |
Immunogen | Synthetic Human CGRP (Peninsula) |
Specificity | Absorption with 10-100 µg CGRP per ml diluted antiserum abolishes the staining, while while calcitonin does not. Cross-reacts with amylin (IAPP). |
Formulation | State: Serum State: Lyophilized Serum |
Reconstitution Method | Dissolve the antiserum in 50-100 μl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09 Sodium Azide. |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Gene Name | calcitonin related polypeptide alpha |
Database Link | |
Background | The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP. |
Synonyms | Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I |
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