PTTG1IP Rabbit Polyclonal Antibody

CAT#: AP31754PU-N

PTTG1IP rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from RAW264.7 cells, using. The lane on the right is treated with the synthesized peptide.

• 

  Human Prostate, Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from Human PTTG.
  Epitope: Internal.
• Specificity: This antibody detects endogenous levels of total PTTG protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: pituitary tumor-transforming 1 interacting protein
• Database Link:
  Entrez Gene 108705 MouseEntrez Gene 365548 RatEntrez Gene 754 Human
  UniProt ID P53801
• Background: The encoded protein, which directly binds to pituitary tumor-transforming protein-1 (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.
• Synonyms: PTTG-binding factor, PBF, C21orf1, C21orf3

Reference Data

• Protein Families: Druggable Genome, Transmembrane