MMP16 (C-term) Rabbit Polyclonal Antibody

CAT#: AP23329PU-N

MMP16 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

MMP16 Polyclonal Antibody

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  MMP16 Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: At 1-2μg/ml with the appropriate system to detect MMP16 in cells and tissues.
  Immunohistochemistry on paraffin sections: At 0.5-1μg/ml to detect MMP16 in formalin fixed and paraffin embedded tissues.
  Immunohistochemistry on frozen sections: At 0.5-1μg/ml to detect MMP16 in formalin or acetone fixed tissues.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide mapping at the C-terminal of human MMP16
• Specificity: This antibody detects MMP-16 at C-term.
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: matrix metallopeptidase 16
• Database Link:
  Entrez Gene 17389 MouseEntrez Gene 65205 RatEntrez Gene 4325 Human
  UniProt ID P51512
• Background: The matrix metalloproteinase 16(MMP16) protein consists of 604 amino acids and has a characteristic MMP domain structure, which gene is mapped on human chromosome 8q211. Additionally, MMP16 has a C-terminal extension containing a potential transmembrane domain, similar to MMP14 , MMP15 , and MMP172. Furthermore, it is membrane-bound and is a member of the membrane-type MMPs that are a subclass in the MMP family since the other members lack a C-terminal transmembrane domain and are secreted as soluble forms. MMP16 is expressed as a 12-kb transcript in brain, placenta, heart, and some carcinoma cell lines, but is not detectably expressed in lung, kidney, liver, spleen, and muscle.
• Synonyms: Matrix metalloproteinase-16, MMP-X2, MMP16, MMPX2, Membrane-type-3 matrix metalloproteinase

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane