B Raf (BRAF) pThr400 Rabbit Polyclonal Antibody
Other products for "BRAF"
Specifications
Product Data | |
Recommended Dilution | ELISA: 1/1,000. Dot Blot: 1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF. |
Specificity | This antibody detects B-Raf proto-oncogene (BRAF) pThr400. Predicted to cross react with Mouse (100% Antigen Homology). |
Formulation | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein A Chromatography followed by two-step phosphospecific peptide affinity purification. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | B-Raf proto-oncogene, serine/threonine kinase |
Database Link | |
Background | BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer. |
Synonyms | BRAF, BRAF1, RAFB1, p94 |
Note | Molecular weight: 84437 Da |
Reference Data |
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