ENT1 (SLC29A1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP11116PU-N

ENT1 (SLC29A1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of ENT1 Antibody (C-term) in mouse heart tissue lysates (35ug/lane). ENT1 (arrow) was detected using the purified Pab (1:300 dilution).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1-100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ENT1.
• Specificity: This antibody is specific to ENT1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: solute carrier family 29 member 1 (Augustine blood group)
• Database Link:
  Entrez Gene 2030 Human
  UniProt ID Q99808
• Background: ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
• Synonyms: ENT1; MGC1465; MGC3778; OTTHUMP00000016509; OTTHUMP00000016510; OTTHUMP00000016511; OTTHUMP00000016512