GRIA1 pSer849 Rabbit Polyclonal Antibody

CAT#: AP02510PU-N

GRIA1 pSer849 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extract from mouse brain tissue, using GluR1 antibody (Lane 1 and 2) and GluR1 (pSer849) antibody (Lane 3 and 4).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1:500~1:1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human GluR1 around the phosphorylation site of serine 849 (Q-Q-SP-I-N ).
• Specificity: GluR1 Antibody detects endogenous levels of GluR1 only when phosphorylated at serine 849.
• Formulation: PBS(without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol
  State: Aff - Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: glutamate ionotropic receptor AMPA type subunit 1
• Database Link:
  Entrez Gene 2890 Human
  UniProt ID P42261
• Background: Glutamate dehydrogenase has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of Glutamate dehydrogenase, is present in brain in concentrations higher than in other organs. In nervous tissue, Glutamate dehydrogenase appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification.
• Synonyms: GluR-1, GRIA1, GLUH1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA1