prothymosin, alpha (PTMA) Rabbit Polyclonal Antibody

CAT#: AP02227SU-S

prothymosin, alpha (PTMA) rabbit polyclonal antibody, Serum

Product Images

Figure 1. Immunofluorescence of Thymosin alpha-1 staining of Paraffin Section of Human juvenile thymus. A: The section was incubated with AP02227SU (1/100) followed by an appropriate secondary antibody coupled to Cy3. The nuclei were stained with DAPI. Original magnification: x20. B: Control Section without primary antibody. Original magnification: x10.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/4000.
  Immunohistochemistry on Frozen Sections: 1/50 (See Ref.1,2).
  Immunohistochemistry on Paraffin Sections: 1/100-1/1000 (See Ref.1,2).
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic Human Thymosin alpha-1,(aa 2-29) KLH conjugated
• Specificity: This antibody detects Thymosin alpha 1.
  There was no cross reactivity obtained against Human Thymosin beta-4 and Human Thymulin.
• Formulation: State: Serum
  State: Lyophilized serum
• Reconstitution Method: Restore in aqua bidest to initial volume
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C and reconstituted at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: prothymosin, alpha
• Database Link:
  Entrez Gene 5757 Human
  UniProt ID P06454
• Background: The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin alpha. A peptide containing 28 amino acid residues, named thymosin alpha 1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and in vivo test systems. Thymosin alpha 1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin alpha 1.
• Synonyms: PTMA, TMSA, Thymosin alpha-1