CD14 Mouse Monoclonal Antibody [Clone ID: B-A8]

CAT#: AM31358AF-N

CD14 mouse monoclonal antibody, clone B-A8, Azide Free


USD 370.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name B-A8
Applications FC
Recommended Dilution Flow Cytometry.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Monocytes.
Specificity Recognises the lipopolysaccharide receptor (LPS R), a 55 kDa protein.
Formulation PBS without Carrier and preservatives.
This product is Sterile-filtered through 0.22 µm and treated to remove endotoxins.
State: Azide Free
State: Liquid purified IgG fraction
Concentration lot specific
Purification Ion Exchange Chromatography
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name CD14 molecule
Background CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
Synonyms CD14
Reference Data
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Hematopoietic cell lineage, MAPK signaling pathway, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Toll-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.