EPM2A Mouse Monoclonal Antibody [Clone ID: k2A3]

CAT#: AM09050PU-N

EPM2A mouse monoclonal antibody, clone k2A3, Purified

Product Images

Cell lysates of HeLa and 293T (20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human EPM2A (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

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  Western blot analysis: Cell lysates of HeLa and 293T (20 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human EPM2A (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: k2A3
• Applications: ELISA, FC, WB
• Recommended Dilution: ELISA.
  Western blot (1/1,000-1/2,000).
  Flow Cytometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human EPM2A (aa 243-331) purified from E. coli
• Specificity: The antibody recognizes EPM2A.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
• Database Link:
  Entrez Gene 7957 Human
  UniProt ID O95278
• Background: Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules.
  Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2(EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy.
• Synonyms: EPM2A, Laforin, EC=3.1.3.48, EC=3.1.3.16, Lafora PTPase, LAFPTPase