Cytokeratin 19 (KRT19) Mouse Monoclonal Antibody [Clone ID: 1H6]

CAT#: AM06638SU-N

Cytokeratin 19 (KRT19) mouse monoclonal antibody, clone 1H6, Ascites

Product Images

Western blot analysis using KRT19 mouse mAb against T47D (1), MCF-7 (2), SKBR-3 (3), HepG2 (4), Caco-2 (5) and SW620 (6) cell lysate.

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  Red: Control Antigen (100ng) Purple: Antigen (10ng) Green: Antigen (50ng) Blue: Antigen (100ng)

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  Immunohistochemical analysis of paraffin-embedded rectum cancer tissues (left) and lung cancer tissues (right) using KRT19 mouse mAb with DAB staining.

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  Immunohistochemical analysis of paraffin-embedded stomach cancer tissues (left) and stomach tissues (right) using KRT19 mouse mAb with DAB staining.

Specifications

Product Data

• Clone Name: 1H6
• Applications: ELISA, IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/2000.
  Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human KRT19 expressed in E. Coli.
  
• Specificity: This antibody recognizes KRT19.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 41 kDa
• Gene Name: keratin 19
• Database Link:
  Entrez Gene 3880 Human
  UniProt ID P08727
• Background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
• Synonyms: Cytokeratin-19, Keratin-19, KRT19, CK19, K19