PSIP1 Mouse Monoclonal Antibody [Clone ID: 6E4]

CAT#: AM06564SU-N

PSIP1 mouse monoclonal antibody, clone 6E4, Ascites

Product Images

Western blot analysis using PSIP1 antibody Cat.-No AM06564SU-N against HepG2 (1), Jurkat (2), K562 (3), Cos7 (4), PC-12 (5), Hela (6), and NIH/3T3 (7) cell lysate.

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  Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and brain tissues (right) using PSIP1 antibody Cat.-No AM06564SU-N with DAB staining.

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  Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and ovarian cancer tissues (right) using PSIP1 antibody Cat.-No AM06564SU-N with DAB staining.

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  Immunofluorescence analysis of NIH/3T3 cells using PSIP1 antibody Cat.-No AM06564SU-N (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

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Specifications

Product Data

• Clone Name: 6E4
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
  Immunofluorescence: 1/200 - 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivities: Human, Monkey, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human PSIP1 expressed in E. Coli.
• Specificity: Recognizes PSIP1
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 75 kDa
• Gene Name: PC4 and SFRS1 interacting protein 1
• Database Link:
  Entrez Gene 11168 Human
  UniProt ID O75475
• Background: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.
• Synonyms: PSIP1, DFS70, LEDGF, PSIP2, PC4 and SFRS1-interacting protein, DFS 70, CLL-associated antigen KW-7