PD1 (PDCD1) (21-167) Mouse Monoclonal Antibody [Clone ID: 4F12]
Other products for "PDCD1"
Specifications
Product Data | |
Clone Name | 4F12 |
Applications | ELISA, WB |
Recommended Dilution | ELISA. Western blot: 1/500 (starting dilution) - 1/1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant human PDCD1 (21-167aa) purified from E. coli |
Specificity | This antibody detects PDCD1. |
Formulation | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | programmed cell death 1 |
Database Link | |
Background | PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases. |
Synonyms | Protein PD-1, hPD-1, PDCD1 |
Reference Data |
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