BNP (NPPB) (NT-proBNP 1-21) Mouse Monoclonal Antibody [Clone ID: 27-4-3]

CAT#: AM02179PU-S

BNP (NPPB) (NT-proBNP 1-21) mouse monoclonal antibody, clone 27-4-3, Purified

Specifications

Product Data

• Clone Name: 27-4-3
• Applications: ELISA
• Recommended Dilution: ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Synthetic human pro-BNP (aa 1-21) poly Lysin conjugated
• Specificity: This antibody detects synthetic pro-BNP (aa 1-21)
• Formulation: 200 mM Na Citrat / TRIS, 500 mM NaCl buffer pH 7;5 0,02% NaN3
  State: Purified
  State: Lyophilized IgG fraction
• Reconstitution Method: Restore in aqua bidest to 1 mg/ml.
• Purification: Protein A chromatography
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: natriuretic peptide B
• Database Link:
  Entrez Gene 4879 Human
  UniProt ID P16860
• Background: In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
• Synonyms: NPPB, Brain natriuretic peptide, BNP, proBNP