CD13 (ANPEP) Human Recombinant Protein

CAT#: TP726676

Recombinant Human APN Protein (C-6His)

Specifications

Product Data

• Species: Human
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Lys69­Lys967
• Tag: C-6His
• Buffer: Supplied as a 0.2 um filtered solution of PBS,pH7.4.
• Note: Recombinant Human Aminopeptidase N is produced by our Mammalian expression system and the target gene encoding Lys69­Lys967 is expressed with a 6His tag at the C-terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 290
• UniProt ID: P15144
• Summary: ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.