Cd86 Mouse Recombinant Protein

CAT#: TP724599

Recombinant Mouse CD86

Specifications

Product Data

• Species: Mouse
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Val24-Lys244
• Tag: C-His
• Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Note: Recombinant Mouse T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Val24-Lys244 is expressed with a 6His tag at the C-terminus.
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 12524
• UniProt ID: P42082
• Summary: T-lymphocyte activation antigen CD86 (B7-2) is a type I membrane protein that belongs to the B7 family. CD86 is highly expressed on activated antigen presenting cells. CD86 plays an essential role for T-lymphocyte proliferation and interleukin-2 production through binding CD28 or CTLA-4. It is also involved in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Additionally, the CD86 participates innate immune responses by activating NF-?B-signaling pathway in macrophages. CD86 thus is predicted to be a promising candidate for immune therapy.