Mouse Tars2 activation kit by CRISPRa

CAT#: GA208957

Tars2 CRISPRa kit - CRISPR gene activation of mouse threonyl-tRNA synthetase 2, mitochondrial (putative)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Tars2
• Locus ID: 71807
• Kit Components:

  GA208957G1, Tars2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208957G2, Tars2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208957G3, Tars2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163617, NM_001163618, NM_001163619, NM_027931, NM_001356965, NM_001356966, NM_001356967, NR_151588, NR_151589
• UniProt ID: Q3UQ84
• Synonyms: 2610024N01Rik; AI429208; Tarsl1
• Summary: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.[UniProtKB/Swiss-Prot Function]