Mouse Pycr2 activation kit by CRISPRa

CAT#: GA208033

Pycr2 CRISPRa kit - CRISPR gene activation of mouse pyrroline-5-carboxylate reductase family, member 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Pycr2
• Locus ID: 69051
• Kit Components:

  GA208033G1, Pycr2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208033G2, Pycr2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208033G3, Pycr2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_133705
• UniProt ID: Q922Q4
• Synonyms: 1810018M05Rik; P5cr2
• Summary: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity). Involved in cellular response to oxidative stress (By similarity).[UniProtKB/Swiss-Prot Function]